N-myristoyltransferase: A potential novel diagnostic marker for colon cancer

N-myristoyltransferase: A potential novel diagnostic marker for colon cancer

<p>Abstract</p> <p>Background</p> <p>Colon cancer is the second leading cause of cancer deaths in the western world. If detected early, colorectal cancer is one of the most treatable forms of cancer. Unfortunately, very few people are screened. N-myristoyltransferase (N...

Full description

Bibliographic Details
Main Authors:	DeCoteau John, Saxena Anurag, Varma Shailly, Shrivastav Anuraag, Sharma Rajendra K
Format:	Article
Language:	English
Published:	BMC 2007-11-01
Series:	Journal of Translational Medicine
Online Access:	http://www.translational-medicine.com/content/5/1/58

Similar Items

In silico identification of microRNAs predicted to regulate N-myristoyltransferase and Methionine Aminopeptidase 2 functions in cancer and infectious diseases.
by: Ranjit Chauhan, et al.
Published: (2018-01-01)

The Potential Use of N-Myristoyltransferase as a Biomarker in the Early Diagnosis of Colon Cancer
by: Rajendra K Sharma, et al.
Published: (2011-03-01)

N-myristoyltransferase 2–based Blood Test for the Detection of Colorectal Adenomatous Polyps and Cancer
by: Tharmini Rathinagopal, LNP, MSc, et al.
Published: (2022-03-01)

Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3): Unraveling the Role in Mediating IGF-Independent Effects Within the Cell
by: Shailly Varma Shrivastav, et al.
Published: (2020-05-01)

N-terminal region of the catalytic domain of human N-myristoyltransferase 1 acts as an inhibitory module.
by: Sujeet Kumar, et al.
Published: (2015-01-01)

N-myristoyltransferase1 and N-myristoyltransferase2 Exhibit Differential Substrate Specificity for HIV-Gag and HIV-Nef
by: Smith Charles, et al.
Published: (2005-12-01)

Insulin-Like Growth Factor Binding Protein-3 Binds to Histone 3
by: Apurva Bhardwaj, et al.
Published: (2021-01-01)

The role of N-myristoyltransferase 1 in tumour development
by: Hong Wang, et al.
Published: (2023-12-01)

Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening
by: Danislav S. Spassov, et al.
Published: (2022-08-01)

QSAR Study of N-Myristoyltransferase Inhibitors of Antimalarial Agents
by: Letícia Santos-Garcia, et al.
Published: (2018-09-01)

Exploring Novel N‑Myristoyltransferase Inhibitors: A Molecular Dynamics Simulation Approach
by: Ruqaiya Khalil, et al.
Published: (2019-08-01)

N-Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus
by: Yu Wang, et al.
Published: (2023-02-01)

Myristoylation: An Important Protein Modification in the Immune Response
by: Daniel Ikenna Udenwobele, et al.
Published: (2017-06-01)

Inhibitor Trapping in N-Myristoyltransferases as a Mechanism for Drug Potency
by: Danislav S. Spassov, et al.
Published: (2023-07-01)

Inhibition of N‐myristoyltransferase1 affects dengue virus replication
by: San Suwanmanee, et al.
Published: (2019-09-01)

Analyzing a potential drug target N-myristoyltransferase of Plasmodium falciparum through in silico approaches
by: Amit Kumar Banerjee, et al.
Published: (2012-01-01)

N-Myristoyltransferases as antileishmanial targets: a piggyback approach with benzoheterocyclic analogues
by: Luis Otávio Junqueira, et al.
Published: (2019-10-01)

Discovery of Novel Myristic Acid Derivatives as N-Myristoyltransferase Inhibitors: Design, Synthesis, Analysis, Computational Studies and Antifungal Activity
by: Saleem Javid, et al.
Published: (2023-07-01)

Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts
by: Diego Rodríguez-Hernández, et al.
Published: (2023-09-01)

A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors
by: Danislav S. Spassov, et al.
Published: (2023-01-01)

Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs.
by: Andrew S Bell, et al.
Published: (2012-01-01)

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model
by: Daniel Paape, et al.
Published: (2020-03-01)

QSAR and Pharmacophore Modeling of Nitrogen Heterocycles as Potent Human <i>N</i>-Myristoyltransferase (Hs-NMT) Inhibitors
by: Magdi E. A. Zaki, et al.
Published: (2021-03-01)

A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes.
by: Brendan D Galvin, et al.
Published: (2014-09-01)

Cellular N-myristoyltransferases play a crucial picornavirus genus-specific role in viral assembly, virion maturation, and infectivity.
by: Irena Corbic Ramljak, et al.
Published: (2018-08-01)

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
by: Tatsiana Kosciuk, et al.
Published: (2020-02-01)

Identification of Potential <i>Leishmania</i> N-Myristoyltransferase Inhibitors from <i>Withania somnifera</i> (L.) Dunal: A Molecular Docking and Molecular Dynamics Investigation
by: Mohamed A. A. Orabi, et al.
Published: (2023-01-01)

Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA[S]
by: Eric Soupene, et al.
Published: (2016-02-01)

Alterations in Gene Pair Correlations as Potential Diagnostic Markers for Colon Cancer
by: Bonnie Yang Yang, et al.
Published: (2022-10-01)

Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry.
by: Lalita Priyamvada, et al.
Published: (2022-10-01)

Promising Diagnostic Markers of Colon Cancer
by: S. V. Volkov, et al.
Published: (2021-06-01)

SPI1 Mediates N-Myristoyltransferase 1 to Advance Gastric Cancer Progression via PI3K/AKT/mTOR Pathway
by: Ping Qiu, et al.
Published: (2023-01-01)

Triethylammonium N′-(benzylsulfanylthiocarbonyl)-2-hydroxybenzohydrazidate
by: Ajay K. Srivastava, et al.
Published: (2008-01-01)

Imaging Immune Cells Using Fc Domain Probes in Mouse Cancer Xenograft Models
by: Wendy Bernhard, et al.
Published: (2022-01-01)

Homotypic Entosis as a Potential Novel Diagnostic Marker in Breast Cancer
by: Ireneusz Dziuba, et al.
Published: (2023-04-01)

RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression
by: Torlakovic Emina, et al.
Published: (2009-07-01)

Characterisation of tetraspanins from Schistosoma haematobium and evaluation of their potential as novel diagnostic markers.
by: Gebeyaw G Mekonnen, et al.
Published: (2022-01-01)

Stable Encoding of Task Structure Coexists with Flexible Coding of Task Sensorimotor Striatum
by: Kubota, Yasuo, et al.
Published: (2011)

Potential novel markers in IBD and CRC diagnostics. Are MMP-19 and RAGE promising candidates?
by: Pavel Horak, et al.
Published: (2022-12-01)

Long Noncoding RNA SNHG7 Is a Diagnostic and Prognostic Marker for Colon Adenocarcinoma
by: Chengwei Jiang, et al.
Published: (2022-06-01)