Multivariate analysis of the effect of Chalazia on astigmatism in children
Abstract Background Chalazion may affect visual acuity. This study aimed to evaluate refractive status of chalazia and effect of different sites, sizes, and numbers of chalazion on astigmatism. Methods Three hundred ninety-eight patients aged 0.5–6 years were divided into the chalazion group (491 ey...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02529-1 |
| _version_ | 1818198229022408704 |
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| author | Lijuan Ouyang Xinke Chen Lianhong Pi Ning Ke |
| author_facet | Lijuan Ouyang Xinke Chen Lianhong Pi Ning Ke |
| author_sort | Lijuan Ouyang |
| collection | DOAJ |
| description | Abstract Background Chalazion may affect visual acuity. This study aimed to evaluate refractive status of chalazia and effect of different sites, sizes, and numbers of chalazion on astigmatism. Methods Three hundred ninety-eight patients aged 0.5–6 years were divided into the chalazion group (491 eyes) and the control group (305 eyes). Chalazia were classified according to the site, size, and number. Refractive status was analyzed through the comparison of incidence, type, mean value and vector analysis. Results The incidence, type, refractive mean and of astigmatism in the chalazion group were higher than those in the control group, and the difference was statistically significant (P < 0.05). For comparison of the incidence, the middle-upper eyelid (50%) was highest, followed by 41.77% in the medial-upper eyelid, both higher than that in the control group (P < 0.05). In medium (54.55%) and large groups (54.76%) were higher than that in the control group (27.21%) (P < 0.05). In multiple chalazia, the astigmatism incidence for chalazion with two masses was highest (56%), much higher than that in the control group (P < 0.05). However, this difference was not significant in chalazion with ≥3 masses (P > 0.05). For comparison of the refractive mean,the medial-upper eyelid, middle-upper eyelid and medial-lower eyelid were higher than the control group (P < 0.05) (P < 0.05). The 3-5 mm and >5 mm group were higher than those in the control group and <3 mm group(P < 0.05), and the>5 mm group was larger than the 3-5 mm group，suggesting that the risk of astigmatism was higher when the size of masses > 5 mm. Astigmatism vector analysis can intuitively show the differences between groups, the results are the same as refractive astigmatism. Conclusion Chalazia in children can easily lead to astigmatism, especially AR and OBL. Chalazia in the middle-upper eyelid, size ≥3 mm, and multiple chalazia (especially two masses) are risk factors of astigmatism. Invasive treatment should be performed promptly if conservative treatment cannot avoid further harm to the visual acuity due to astigmatism. |
| first_indexed | 2024-12-12T02:02:33Z |
| format | Article |
| id | doaj.art-5af3157d1fea4091877ff447c64f6c6e |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-12T02:02:33Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-5af3157d1fea4091877ff447c64f6c6e2022-12-22T00:42:07ZengBMCBMC Ophthalmology1471-24152022-07-0122111010.1186/s12886-022-02529-1Multivariate analysis of the effect of Chalazia on astigmatism in childrenLijuan Ouyang0Xinke Chen1Lianhong Pi2Ning Ke3Department of Ophthalmology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders. China International Science and Technology Cooperation base of Child Development and Critical Disorders. Chongqing Key Laboratory of PediatricsDepartment of Ophthalmology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders. China International Science and Technology Cooperation base of Child Development and Critical Disorders. Chongqing Key Laboratory of PediatricsDepartment of Ophthalmology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders. China International Science and Technology Cooperation base of Child Development and Critical Disorders. Chongqing Key Laboratory of PediatricsDepartment of Ophthalmology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders. China International Science and Technology Cooperation base of Child Development and Critical Disorders. Chongqing Key Laboratory of PediatricsAbstract Background Chalazion may affect visual acuity. This study aimed to evaluate refractive status of chalazia and effect of different sites, sizes, and numbers of chalazion on astigmatism. Methods Three hundred ninety-eight patients aged 0.5–6 years were divided into the chalazion group (491 eyes) and the control group (305 eyes). Chalazia were classified according to the site, size, and number. Refractive status was analyzed through the comparison of incidence, type, mean value and vector analysis. Results The incidence, type, refractive mean and of astigmatism in the chalazion group were higher than those in the control group, and the difference was statistically significant (P < 0.05). For comparison of the incidence, the middle-upper eyelid (50%) was highest, followed by 41.77% in the medial-upper eyelid, both higher than that in the control group (P < 0.05). In medium (54.55%) and large groups (54.76%) were higher than that in the control group (27.21%) (P < 0.05). In multiple chalazia, the astigmatism incidence for chalazion with two masses was highest (56%), much higher than that in the control group (P < 0.05). However, this difference was not significant in chalazion with ≥3 masses (P > 0.05). For comparison of the refractive mean,the medial-upper eyelid, middle-upper eyelid and medial-lower eyelid were higher than the control group (P < 0.05) (P < 0.05). The 3-5 mm and >5 mm group were higher than those in the control group and <3 mm group(P < 0.05), and the>5 mm group was larger than the 3-5 mm group，suggesting that the risk of astigmatism was higher when the size of masses > 5 mm. Astigmatism vector analysis can intuitively show the differences between groups, the results are the same as refractive astigmatism. Conclusion Chalazia in children can easily lead to astigmatism, especially AR and OBL. Chalazia in the middle-upper eyelid, size ≥3 mm, and multiple chalazia (especially two masses) are risk factors of astigmatism. Invasive treatment should be performed promptly if conservative treatment cannot avoid further harm to the visual acuity due to astigmatism.https://doi.org/10.1186/s12886-022-02529-1AstigmatismAmblyopiaChalazionDouble-angle plotsPreschool children |
| spellingShingle | Lijuan Ouyang Xinke Chen Lianhong Pi Ning Ke Multivariate analysis of the effect of Chalazia on astigmatism in children BMC Ophthalmology Astigmatism Amblyopia Chalazion Double-angle plots Preschool children |
| title | Multivariate analysis of the effect of Chalazia on astigmatism in children |
| title_full | Multivariate analysis of the effect of Chalazia on astigmatism in children |
| title_fullStr | Multivariate analysis of the effect of Chalazia on astigmatism in children |
| title_full_unstemmed | Multivariate analysis of the effect of Chalazia on astigmatism in children |
| title_short | Multivariate analysis of the effect of Chalazia on astigmatism in children |
| title_sort | multivariate analysis of the effect of chalazia on astigmatism in children |
| topic | Astigmatism Amblyopia Chalazion Double-angle plots Preschool children |
| url | https://doi.org/10.1186/s12886-022-02529-1 |
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