Biohybrid materials: Structure design and biomedical applications

Biohybrid materials are proceeded by integrating living cells and non-living materials to endow materials with biomimetic properties and functionalities by supporting cell proliferation and even enhancing cell functions. Due to the outstanding biocompatibility and programmability, biohybrid material...

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Main Authors: Chong Wang, Zhuohao Zhang, Jiali Wang, Qiao Wang, Luoran Shang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422001508
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author Chong Wang
Zhuohao Zhang
Jiali Wang
Qiao Wang
Luoran Shang
author_facet Chong Wang
Zhuohao Zhang
Jiali Wang
Qiao Wang
Luoran Shang
author_sort Chong Wang
collection DOAJ
description Biohybrid materials are proceeded by integrating living cells and non-living materials to endow materials with biomimetic properties and functionalities by supporting cell proliferation and even enhancing cell functions. Due to the outstanding biocompatibility and programmability, biohybrid materials provide some promising strategies to overcome current problems in the biomedical field. Here, we review the concept and unique features of biohybrid materials by comparing them with conventional materials. We emphasize the structure design of biohybrid materials and discuss the structure-function relationships. We also enumerate the application aspects of biohybrid materials in biomedical frontiers. We believe this review will bring various opportunities to promote the communication between cell biology, material sciences, and medical engineering.
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spelling doaj.art-5af35fd030884e699d1c72c8c04cfc892022-12-22T03:34:02ZengElsevierMaterials Today Bio2590-00642022-12-0116100352Biohybrid materials: Structure design and biomedical applicationsChong Wang0Zhuohao Zhang1Jiali Wang2Qiao Wang3Luoran Shang4Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, And the Shanghai Key Laboratory of Medical Epigenetics, The International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, ChinaShanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, And the Shanghai Key Laboratory of Medical Epigenetics, The International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, ChinaShanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, And the Shanghai Key Laboratory of Medical Epigenetics, The International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, ChinaShanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, And the Shanghai Key Laboratory of Medical Epigenetics, The International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, ChinaCorresponding author.; Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, And the Shanghai Key Laboratory of Medical Epigenetics, The International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, ChinaBiohybrid materials are proceeded by integrating living cells and non-living materials to endow materials with biomimetic properties and functionalities by supporting cell proliferation and even enhancing cell functions. Due to the outstanding biocompatibility and programmability, biohybrid materials provide some promising strategies to overcome current problems in the biomedical field. Here, we review the concept and unique features of biohybrid materials by comparing them with conventional materials. We emphasize the structure design of biohybrid materials and discuss the structure-function relationships. We also enumerate the application aspects of biohybrid materials in biomedical frontiers. We believe this review will bring various opportunities to promote the communication between cell biology, material sciences, and medical engineering.http://www.sciencedirect.com/science/article/pii/S2590006422001508Biohybrid sheetBiohybrid fiberBiohybrid microgelBiohybrid microcapsuleBiohybrid scaffold
spellingShingle Chong Wang
Zhuohao Zhang
Jiali Wang
Qiao Wang
Luoran Shang
Biohybrid materials: Structure design and biomedical applications
Materials Today Bio
Biohybrid sheet
Biohybrid fiber
Biohybrid microgel
Biohybrid microcapsule
Biohybrid scaffold
title Biohybrid materials: Structure design and biomedical applications
title_full Biohybrid materials: Structure design and biomedical applications
title_fullStr Biohybrid materials: Structure design and biomedical applications
title_full_unstemmed Biohybrid materials: Structure design and biomedical applications
title_short Biohybrid materials: Structure design and biomedical applications
title_sort biohybrid materials structure design and biomedical applications
topic Biohybrid sheet
Biohybrid fiber
Biohybrid microgel
Biohybrid microcapsule
Biohybrid scaffold
url http://www.sciencedirect.com/science/article/pii/S2590006422001508
work_keys_str_mv AT chongwang biohybridmaterialsstructuredesignandbiomedicalapplications
AT zhuohaozhang biohybridmaterialsstructuredesignandbiomedicalapplications
AT jialiwang biohybridmaterialsstructuredesignandbiomedicalapplications
AT qiaowang biohybridmaterialsstructuredesignandbiomedicalapplications
AT luoranshang biohybridmaterialsstructuredesignandbiomedicalapplications