Association between the rs615563 variant of PCSK9 gene and circulating lipids and Type 2 diabetes

Association between the rs615563 variant of PCSK9 gene and circulating lipids and Type 2 diabetes

Abstract Objective Many different genetic variants of proprotein convertase subtilisin kexin 9 (PCSK9) are related to the serum levels of cholesterol and LDL cholesterol (LDL-C). The rs615563 variant of PCSK9 (a gain-of-function mutation) is associated with increased triglycerides and cholesterol le...

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Bibliographic Details
Main Authors: Samira Taghizadeh Jazdani, Hajieh Bibi Shahbazian, Bahman Cheraghian, Mohammad Taha Jalali, Narges Mohammadtaghvaei
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Research Notes
Subjects:
Type 2 diabetes
LDL cholesterol
rs615563
PCSK9
PCR–RFLP
Online Access:https://doi.org/10.1186/s13104-021-05723-4

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