A synthetic human 3D in vitro lymphoid model enhancing B-cell survival and functional differentiation

A synthetic human 3D in vitro lymphoid model enhancing B-cell survival and functional differentiation

Summary: To investigate B-cell differentiation and maturation occurring in the germinal center (GC) using in vitro culture systems, key factors and interactions of the GC reaction need to be accurately simulated. This study aims at improving in vitro GC simulation using 3D culture techniques. Human...

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Bibliographic Details
Main Authors: Maaike V.J. Braham, Rob S. van Binnendijk, Anne-Marie M. Buisman, Reina E. Mebius, Jelle de Wit, Cécile A.C.M. van Els
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Biological sciences
Bioengineering
Cell engineering
Tissue Engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222020144

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