Rosiglitazone Protects Endothelial Cells From Irradiation-Induced Mitochondrial Dysfunction

Rosiglitazone Protects Endothelial Cells From Irradiation-Induced Mitochondrial Dysfunction

Background and PurposeUp to 50–60% of all cancer patients receive radiotherapy as part of their treatment strategy. However, the mechanisms accounting for increased vascular risks after irradiation are not completely understood. Mitochondrial dysfunction has been identified as a potential cause of r...

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Bibliographic Details
Main Authors: Bjorn Baselet, Ronald B. Driesen, Emma Coninx, Niels Belmans, Tom Sieprath, Ivo Lambrichts, Winnok H. De Vos, Sarah Baatout, Pierre Sonveaux, An Aerts
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
ionizing radiation
endothelial cells
rosiglitazone
mitochondria
cardiovascular disease
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00268/full

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