Characteristics of an advanced epilepsy treatment gap in a region in Japan
To investigate the quality of epilepsy care in a region in Japan that lacked specialised care, we retrospectively evaluated patients who visited our newly established epilepsy division between April 2018 and March 2021, and had been treated with anti-seizure medications (ASMs) for at least 1 year pr...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Epilepsy & Behavior Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589986423000461 |
| _version_ | 1797400862899830784 |
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| author | Tetsuhiro Fukuyama Manami Yabe Makoto Nishioka Takenori Natsume Yuumi Hoshino Kohei Kanaya Kyoko Takano Norimoto Kobayashi Yushi Inoue |
| author_facet | Tetsuhiro Fukuyama Manami Yabe Makoto Nishioka Takenori Natsume Yuumi Hoshino Kohei Kanaya Kyoko Takano Norimoto Kobayashi Yushi Inoue |
| author_sort | Tetsuhiro Fukuyama |
| collection | DOAJ |
| description | To investigate the quality of epilepsy care in a region in Japan that lacked specialised care, we retrospectively evaluated patients who visited our newly established epilepsy division between April 2018 and March 2021, and had been treated with anti-seizure medications (ASMs) for at least 1 year prior.Of the 231 patients included, 169 had ongoing seizure episodes at first visit (seizure-persist group) and 62 had no seizure episodes for more than a year (seizure-free group). Eighty-three patients in the seizure-persist group had not received specialised epilepsy care, 15 had been treated with unnecessary medications, and seven had experienced side effects from ASMs. Twelve patients in the seizure-free group had been treated with unnecessary ASMs, 10 had been treated with ASMs with teratogenic potential and four had experienced ASM side effects. These patients could be classified as having an advanced epilepsy treatment gap (ETG) because they had not previously received necessary specialised care. The progressive decline in the number of patients with advanced ETG suggests that our new epilepsy division has addressed this issue.This study highlights that a significant number of patients with advanced ETGs exist in Japan and that proper countermeasures are required to address this gap. |
| first_indexed | 2024-03-09T02:01:43Z |
| format | Article |
| id | doaj.art-5afb44b1ad29461d8de4eb5a021dc611 |
| institution | Directory Open Access Journal |
| issn | 2589-9864 |
| language | English |
| last_indexed | 2024-03-09T02:01:43Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Epilepsy & Behavior Reports |
| spelling | doaj.art-5afb44b1ad29461d8de4eb5a021dc6112023-12-08T04:45:52ZengElsevierEpilepsy & Behavior Reports2589-98642023-01-0124100628Characteristics of an advanced epilepsy treatment gap in a region in JapanTetsuhiro Fukuyama0Manami Yabe1Makoto Nishioka2Takenori Natsume3Yuumi Hoshino4Kohei Kanaya5Kyoko Takano6Norimoto Kobayashi7Yushi Inoue8Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan; Division of Epilepsy, Shinshu University Hospital, Matsumoto, Japan; Corresponding author at: Department of Pediatrics, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, JapanDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, JapanDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, JapanDivision of Epilepsy, Shinshu University Hospital, Matsumoto, Japan; Department of Neurology, Shinshu University School of Medicine, Matsumoto, JapanDivision of Epilepsy, Shinshu University Hospital, Matsumoto, Japan; Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, JapanCenter of Medical Genetics, Shinshu University Hospital, Matsumoto, JapanDepartment of Pediatrics, Nagano Red Cross Hospital, Nagano, JapanNational Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders, JapanTo investigate the quality of epilepsy care in a region in Japan that lacked specialised care, we retrospectively evaluated patients who visited our newly established epilepsy division between April 2018 and March 2021, and had been treated with anti-seizure medications (ASMs) for at least 1 year prior.Of the 231 patients included, 169 had ongoing seizure episodes at first visit (seizure-persist group) and 62 had no seizure episodes for more than a year (seizure-free group). Eighty-three patients in the seizure-persist group had not received specialised epilepsy care, 15 had been treated with unnecessary medications, and seven had experienced side effects from ASMs. Twelve patients in the seizure-free group had been treated with unnecessary ASMs, 10 had been treated with ASMs with teratogenic potential and four had experienced ASM side effects. These patients could be classified as having an advanced epilepsy treatment gap (ETG) because they had not previously received necessary specialised care. The progressive decline in the number of patients with advanced ETG suggests that our new epilepsy division has addressed this issue.This study highlights that a significant number of patients with advanced ETGs exist in Japan and that proper countermeasures are required to address this gap.http://www.sciencedirect.com/science/article/pii/S2589986423000461Advanced epilepsy treatment gapEpilepsy care systemPseudo-drug-resistant epilepsySpecialised epilepsy care |
| spellingShingle | Tetsuhiro Fukuyama Manami Yabe Makoto Nishioka Takenori Natsume Yuumi Hoshino Kohei Kanaya Kyoko Takano Norimoto Kobayashi Yushi Inoue Characteristics of an advanced epilepsy treatment gap in a region in Japan Epilepsy & Behavior Reports Advanced epilepsy treatment gap Epilepsy care system Pseudo-drug-resistant epilepsy Specialised epilepsy care |
| title | Characteristics of an advanced epilepsy treatment gap in a region in Japan |
| title_full | Characteristics of an advanced epilepsy treatment gap in a region in Japan |
| title_fullStr | Characteristics of an advanced epilepsy treatment gap in a region in Japan |
| title_full_unstemmed | Characteristics of an advanced epilepsy treatment gap in a region in Japan |
| title_short | Characteristics of an advanced epilepsy treatment gap in a region in Japan |
| title_sort | characteristics of an advanced epilepsy treatment gap in a region in japan |
| topic | Advanced epilepsy treatment gap Epilepsy care system Pseudo-drug-resistant epilepsy Specialised epilepsy care |
| url | http://www.sciencedirect.com/science/article/pii/S2589986423000461 |
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