Single-Nucleotide Variants in the AIM2 – Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis

Single-Nucleotide Variants in the AIM2 – Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis

Tuberculosis (TB) remains a serious public health burden worldwide. TB is an infectious disease caused by the Mycobacterium tuberculosis Complex. Innate immune response is critical for controlling mycobacterial infection. NOD-like receptor pyrin domain containing 3/ absent in melanoma 2 (NLRP3/AIM2)...

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Bibliographic Details
Main Authors: Mariana Brasil de Andrade Figueira, Dhêmerson Souza de Lima, Antonio Luiz Boechat, Milton Gomes do Nascimento Filho, Irineide Assumpção Antunes, Joycenéa da Silva Matsuda, Thaís Rodrigues de Albuquerque Ribeiro, Luana Sousa Felix, Ariane Senna Fonseca Gonçalves, Allyson Guimarães da Costa, Rajendranath Ramasawmy, Alessandra Pontillo, Mauricio Morishi Ogusku, Aya Sadahiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
inflammasome
SNV
AIM2
CARD8
CTSB
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.604975/full

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