Spaced Training Enhances Contextual Fear Memory via Activating Hippocampal 5-HT2A Receptors

Spaced Training Enhances Contextual Fear Memory via Activating Hippocampal 5-HT2A Receptors

Spaced training is robustly superior to massed training, which is a well-documented phenomenon in humans and animals. However, the mechanisms underlying the spacing effect still remain unclear. We have reported previously that spacing training exerts memory-enhancing effects by inhibiting forgetting...

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Bibliographic Details
Main Authors: Lizhu Jiang, Liping Wang, Yan Yin, Mengke Huo, Chao Liu, Qixin Zhou, Dafu Yu, Lin Xu, Rongrong Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
spacing effect
5-HT2A receptor
Rac1
hippocampus
contextual fear memory
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00317/full

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