Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice
Secreted isoform of endoplasmic reticulum membrane complex subunit 10 (scEMC10) is a secreted protein of incompletely understood physiological function. Here the authors show that scEMC10 is upregulated in people with obesity, and that that genetic EMC10 deletion or antibody-based neutralization of...
Full description
Bibliographic Details
| Main Authors: |
Xuanchun Wang,
Yanliang Li,
Guifen Qiang,
Kaihua Wang,
Jiarong Dai,
Maximilian McCann,
Marcos D. Munoz,
Victoria Gil,
Yifei Yu,
Shengxian Li,
Zhihong Yang,
Shanshan Xu,
Jose Cordoba-Chacon,
Dario F. De Jesus,
Bei Sun,
Kuangyang Chen,
Yahao Wang,
Xiaoxia Liu,
Qing Miao,
Linuo Zhou,
Renming Hu,
Qiang Ding,
Rohit N. Kulkarni,
Daming Gao,
Matthias Blüher,
Chong Wee Liew |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Portfolio
2022-11-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-022-34259-9
|
|---|