Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells

Abstract Galectin-3 is a galactoside-binding protein that is commonly overexpressed in many epithelial cancers. It is increasingly recognized as a multi-functional, multi-mode promoter in cancer development, progression, and metastasis. This study reports that galectin-3 secretion by human colon can...

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Bibliographic Details
Main Authors: Shun Li, David Mark Pritchard, Lu-Gang Yu
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05789-x

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