SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges
SARS-CoV-2 (COVID-19) has today multiplied globally and various governments are attempting to stop the outbreak of the disease escalation into a worldwide health crisis. At this juncture, readiness, candor, clarity, and partaking of data are of paramount importance to speed up factual evaluation and...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/10/3641 |
| _version_ | 1797567016917270528 |
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| author | Ghazaleh Jamalipour Soufi Ali Hekmatnia Mahmoud Nasrollahzadeh Nasrin Shafiei Mohaddeseh Sajjadi Parisa Iravani Salman Fallah Siavash Iravani Rajender S. Varma |
| author_facet | Ghazaleh Jamalipour Soufi Ali Hekmatnia Mahmoud Nasrollahzadeh Nasrin Shafiei Mohaddeseh Sajjadi Parisa Iravani Salman Fallah Siavash Iravani Rajender S. Varma |
| author_sort | Ghazaleh Jamalipour Soufi |
| collection | DOAJ |
| description | SARS-CoV-2 (COVID-19) has today multiplied globally and various governments are attempting to stop the outbreak of the disease escalation into a worldwide health crisis. At this juncture, readiness, candor, clarity, and partaking of data are of paramount importance to speed up factual evaluation and starting pattern control activities, including serendipitous findings. Owing to the involvement of COVID-19, many facts regarding virulence, pathogenesis, and the real viral infection source and/or transmission mode still need to be addressed. The infected patients often present clinical symptoms with fever, dyspnea, fatigue, diarrhea, vomiting, and dry cough, as well as pulmonary, infiltrates on imaging. Extensive measures to decrease person-to-person transmission of COVID-19 are being implemented to prevent, recognize, and control the current outbreak as it is very similar to SARS-CoV in its clinical spectrum, epidemiology, and pathogenicity. In response to this fatal disease and disruptive outbreak, it is extremely vital to expedite the drug development process to treat the disease and vaccines for the prevention of COVID-19 that would help us defeat this pandemic expeditiously. This paper sums up and unifies the study of virological aspects, disease transmission, clinically administered techniques, therapeutics options, managements, future directions, designing of vaccines, and news dissemination pertaining to COVID-19. |
| first_indexed | 2024-03-10T19:35:38Z |
| format | Article |
| id | doaj.art-5b08fcfdffc3466b99222b867f7d8ce4 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T19:35:38Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-5b08fcfdffc3466b99222b867f7d8ce42023-11-20T01:43:34ZengMDPI AGApplied Sciences2076-34172020-05-011010364110.3390/app10103641SARS-CoV-2 (COVID-19): New Discoveries and Current ChallengesGhazaleh Jamalipour Soufi0Ali Hekmatnia1Mahmoud Nasrollahzadeh2Nasrin Shafiei3Mohaddeseh Sajjadi4Parisa Iravani5Salman Fallah6Siavash Iravani7Rajender S. Varma8Radiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, IranRadiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, IranDepartment of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranDepartment of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranDepartment of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranPediatrics Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, IranPhysical Medicine and Rehabilitation Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746-73461, IranFaculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, IranRegional Centre of Advanced Technologies and Materials, Palacký University in Olomouc, Šlechtitelů 27, 783 71 Olomouc, Czech RepublicSARS-CoV-2 (COVID-19) has today multiplied globally and various governments are attempting to stop the outbreak of the disease escalation into a worldwide health crisis. At this juncture, readiness, candor, clarity, and partaking of data are of paramount importance to speed up factual evaluation and starting pattern control activities, including serendipitous findings. Owing to the involvement of COVID-19, many facts regarding virulence, pathogenesis, and the real viral infection source and/or transmission mode still need to be addressed. The infected patients often present clinical symptoms with fever, dyspnea, fatigue, diarrhea, vomiting, and dry cough, as well as pulmonary, infiltrates on imaging. Extensive measures to decrease person-to-person transmission of COVID-19 are being implemented to prevent, recognize, and control the current outbreak as it is very similar to SARS-CoV in its clinical spectrum, epidemiology, and pathogenicity. In response to this fatal disease and disruptive outbreak, it is extremely vital to expedite the drug development process to treat the disease and vaccines for the prevention of COVID-19 that would help us defeat this pandemic expeditiously. This paper sums up and unifies the study of virological aspects, disease transmission, clinically administered techniques, therapeutics options, managements, future directions, designing of vaccines, and news dissemination pertaining to COVID-19.https://www.mdpi.com/2076-3417/10/10/3641COVID-19diagnosistherapeutics optionscardiovascular systemsrespiratory systemsSARS-CoV-2 |
| spellingShingle | Ghazaleh Jamalipour Soufi Ali Hekmatnia Mahmoud Nasrollahzadeh Nasrin Shafiei Mohaddeseh Sajjadi Parisa Iravani Salman Fallah Siavash Iravani Rajender S. Varma SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges Applied Sciences COVID-19 diagnosis therapeutics options cardiovascular systems respiratory systems SARS-CoV-2 |
| title | SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges |
| title_full | SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges |
| title_fullStr | SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges |
| title_full_unstemmed | SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges |
| title_short | SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges |
| title_sort | sars cov 2 covid 19 new discoveries and current challenges |
| topic | COVID-19 diagnosis therapeutics options cardiovascular systems respiratory systems SARS-CoV-2 |
| url | https://www.mdpi.com/2076-3417/10/10/3641 |
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