Misdiagnosis of renal pelvic unicentric Castleman disease: a case report
Castleman disease is a rare heterogeneous lymphoproliferative disorder of unknown etiology. Unicentric Castleman disease (UCD) is more common. UCD can occur at any site where lymphatic tissue exists, most commonly in the mediastinum, neck, and abdominal cavity, etc. in the current study, we reported...
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1225890/full |
| _version_ | 1797730808544362496 |
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| author | Dian Fu Dian Fu Bo Yang Ming Yang Zhenyu Xu Wen Cheng Zhijia Liu Liming Zhang Zhiguo Mao Cheng Xue |
| author_facet | Dian Fu Dian Fu Bo Yang Ming Yang Zhenyu Xu Wen Cheng Zhijia Liu Liming Zhang Zhiguo Mao Cheng Xue |
| author_sort | Dian Fu |
| collection | DOAJ |
| description | Castleman disease is a rare heterogeneous lymphoproliferative disorder of unknown etiology. Unicentric Castleman disease (UCD) is more common. UCD can occur at any site where lymphatic tissue exists, most commonly in the mediastinum, neck, and abdominal cavity, etc. in the current study, we reported a 46-year-old woman, who has left low back pain and discomfort. Magnetic resonance imaging (MRI) of the kidneys showed the left renal pelvis was occupied, left hydronephrosis, and the left renal hilum and retroperitoneal lymph nodes were enlarged. Enhanced kidney CT showed that the “pelvic tumor” was moderately enhanced in the bottom part in corticomedullary phase, while in nephrogenic phase, it was unevenly enhanced with a highly enhanced bottom part and weakly enhanced upper part. In excretory phase, reinforcement was decreased. “left renal pelvis tumor” was diagnosed and she underwent surgical treatment with left nephrectomy. However, histopathological examination indicated the UCD. We suggest that for renal pelvic tumors having imaging characteristics of homogeneous soft tissue density and heterogeneous CT enhancement, the hyaline vascular type of UCD could be taken into consideration for differential diagnosis. |
| first_indexed | 2024-03-12T11:50:32Z |
| format | Article |
| id | doaj.art-5b0c61f2cb984b60800cad3d6e9f0455 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-12T11:50:32Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-5b0c61f2cb984b60800cad3d6e9f04552023-08-31T09:07:36ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-08-011010.3389/fsurg.2023.12258901225890Misdiagnosis of renal pelvic unicentric Castleman disease: a case reportDian Fu0Dian Fu1Bo Yang2Ming Yang3Zhenyu Xu4Wen Cheng5Zhijia Liu6Liming Zhang7Zhiguo Mao8Cheng Xue9Department of Urology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, ChinaDivision of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, ChinaInternal Medicine III (Nephrology), Naval Medical Center of PLA, Second Military Medical University (Naval Medical University), Shanghai, ChinaDepartment of Nephrology, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, ChinaDepartment of Urology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, ChinaDepartment of Urology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, ChinaDepartment of Urology, 8th medical Center of the PLA General Hospital, Beijing, ChinaDepartment of Nephrology, Zhabei Central Hospital of JingAn District of Shanghai, Shanghai, ChinaDivision of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, ChinaDivision of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, ChinaCastleman disease is a rare heterogeneous lymphoproliferative disorder of unknown etiology. Unicentric Castleman disease (UCD) is more common. UCD can occur at any site where lymphatic tissue exists, most commonly in the mediastinum, neck, and abdominal cavity, etc. in the current study, we reported a 46-year-old woman, who has left low back pain and discomfort. Magnetic resonance imaging (MRI) of the kidneys showed the left renal pelvis was occupied, left hydronephrosis, and the left renal hilum and retroperitoneal lymph nodes were enlarged. Enhanced kidney CT showed that the “pelvic tumor” was moderately enhanced in the bottom part in corticomedullary phase, while in nephrogenic phase, it was unevenly enhanced with a highly enhanced bottom part and weakly enhanced upper part. In excretory phase, reinforcement was decreased. “left renal pelvis tumor” was diagnosed and she underwent surgical treatment with left nephrectomy. However, histopathological examination indicated the UCD. We suggest that for renal pelvic tumors having imaging characteristics of homogeneous soft tissue density and heterogeneous CT enhancement, the hyaline vascular type of UCD could be taken into consideration for differential diagnosis.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1225890/fullCastleman diseaserenal tumordiagnosiscomputerized tomographyimaging |
| spellingShingle | Dian Fu Dian Fu Bo Yang Ming Yang Zhenyu Xu Wen Cheng Zhijia Liu Liming Zhang Zhiguo Mao Cheng Xue Misdiagnosis of renal pelvic unicentric Castleman disease: a case report Frontiers in Surgery Castleman disease renal tumor diagnosis computerized tomography imaging |
| title | Misdiagnosis of renal pelvic unicentric Castleman disease: a case report |
| title_full | Misdiagnosis of renal pelvic unicentric Castleman disease: a case report |
| title_fullStr | Misdiagnosis of renal pelvic unicentric Castleman disease: a case report |
| title_full_unstemmed | Misdiagnosis of renal pelvic unicentric Castleman disease: a case report |
| title_short | Misdiagnosis of renal pelvic unicentric Castleman disease: a case report |
| title_sort | misdiagnosis of renal pelvic unicentric castleman disease a case report |
| topic | Castleman disease renal tumor diagnosis computerized tomography imaging |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1225890/full |
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