Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis

Cardiac fibrosis is a primary contributor to heart failure (HF), and is considered to be a targetable process for HF therapy. Cardiac fibroblast (CF) activation accompanied by excessive extracellular matrix (ECM) production is central to the initiation and maintenance of fibrotic scarring in cardiac...

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Bibliografiska uppgifter
Huvudupphovsmän: Kadiam C. Venkata Subbaiah, Jiangbin Wu, Wai Hong Wilson Tang, Peng Yao
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2023-01-01
Serie:Journal of Cardiovascular Development and Disease
Ämnen:
Länkar:https://www.mdpi.com/2308-3425/10/2/52