Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis
Cardiac fibrosis is a primary contributor to heart failure (HF), and is considered to be a targetable process for HF therapy. Cardiac fibroblast (CF) activation accompanied by excessive extracellular matrix (ECM) production is central to the initiation and maintenance of fibrotic scarring in cardiac...
Huvudupphovsmän: | , , , |
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Materialtyp: | Artikel |
Språk: | English |
Publicerad: |
MDPI AG
2023-01-01
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Serie: | Journal of Cardiovascular Development and Disease |
Ämnen: | |
Länkar: | https://www.mdpi.com/2308-3425/10/2/52 |