Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials
Cancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disp...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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American Society of Clinical Oncology
2021-12-01
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| Series: | JCO Global Oncology |
| Online Access: | https://ascopubs.org/doi/10.1200/GO.21.00096 |
| _version_ | 1828877753390202880 |
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| author | Abiola Ibraheem Colin Pillai Ifeoma Okoye J. Joshua Smith Diane Reidy-Lagunes Grace Macaulay Olusegun Alatise |
| author_facet | Abiola Ibraheem Colin Pillai Ifeoma Okoye J. Joshua Smith Diane Reidy-Lagunes Grace Macaulay Olusegun Alatise |
| author_sort | Abiola Ibraheem |
| collection | DOAJ |
| description | Cancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disparity, globalization of cancer clinical trials to involve sub-Saharan Africa can serve as a platform where innovative targeted therapies can be made available to patients in the environ. In the 2019 African Organization for Research and Training in Cancer (AORTIC) conference held at Maputo, Mozambique, a group of clinical trialists spanning across multiple continents highlighted the opportunities in Africa for the conduct of cancer clinical trials. The secondary purpose of the meeting was to address the belief that Africa was incapable of conducting interventional cancer trials but showed the in-continent strengths, such as available capacities, trained local clinical trialists with clinical trial experiences, clinical trial consortia, local capabilities, mapping out logistics, ethical consideration, political will, real-time benefits of clinical trials to clinical practice, and future directions for trials. |
| first_indexed | 2024-12-13T08:50:19Z |
| format | Article |
| id | doaj.art-5b0f95750cc344848f9b5b7a75b76187 |
| institution | Directory Open Access Journal |
| issn | 2687-8941 |
| language | English |
| last_indexed | 2024-12-13T08:50:19Z |
| publishDate | 2021-12-01 |
| publisher | American Society of Clinical Oncology |
| record_format | Article |
| series | JCO Global Oncology |
| spelling | doaj.art-5b0f95750cc344848f9b5b7a75b761872022-12-21T23:53:23ZengAmerican Society of Clinical OncologyJCO Global Oncology2687-89412021-12-0171358136310.1200/GO.21.00096Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical TrialsAbiola Ibraheem0Colin Pillai1Ifeoma Okoye2J. Joshua Smith3Diane Reidy-Lagunes4Grace Macaulay5Olusegun Alatise6Section of Hematology Oncology, University of Chicago, Chicago, ILDivision of Clinical Pharmacology, University of Cape Town, Cape Town, South AfricaDepartment of Radiology, College of Medicine, University of Nigeria, Nsukka, NigeriaColorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NYGastrointestinal Oncology Service, Department of Medicine, Memorial Department of Medicine, Weill Cornell Medical College, New York, NYMedical Scientific Affairs and Strategy (Oncology), Cepheid Oncology, Sunnyvale, CADivision of Gastrointestinal/Surgical Oncology, Department of Surgery, Obafemi Awolowo University/Teaching Hospitals, Ile-Ife, NigeriaCancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disparity, globalization of cancer clinical trials to involve sub-Saharan Africa can serve as a platform where innovative targeted therapies can be made available to patients in the environ. In the 2019 African Organization for Research and Training in Cancer (AORTIC) conference held at Maputo, Mozambique, a group of clinical trialists spanning across multiple continents highlighted the opportunities in Africa for the conduct of cancer clinical trials. The secondary purpose of the meeting was to address the belief that Africa was incapable of conducting interventional cancer trials but showed the in-continent strengths, such as available capacities, trained local clinical trialists with clinical trial experiences, clinical trial consortia, local capabilities, mapping out logistics, ethical consideration, political will, real-time benefits of clinical trials to clinical practice, and future directions for trials.https://ascopubs.org/doi/10.1200/GO.21.00096 |
| spellingShingle | Abiola Ibraheem Colin Pillai Ifeoma Okoye J. Joshua Smith Diane Reidy-Lagunes Grace Macaulay Olusegun Alatise Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials JCO Global Oncology |
| title | Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials |
| title_full | Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials |
| title_fullStr | Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials |
| title_full_unstemmed | Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials |
| title_short | Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials |
| title_sort | cancer clinical trials in africa an untapped opportunity recommendations from aortic 2019 conference special interest group in clinical trials |
| url | https://ascopubs.org/doi/10.1200/GO.21.00096 |
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