The genetic diversity of Plasmodium vivax: a review

The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vi...

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Main Authors: Wanessa Christina de Souza-Neiras, Luciane Moreno Storti de Melo, Ricardo Luiz Dantas Machado
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2007-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000300002
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author Wanessa Christina de Souza-Neiras
Luciane Moreno Storti de Melo
Ricardo Luiz Dantas Machado
author_facet Wanessa Christina de Souza-Neiras
Luciane Moreno Storti de Melo
Ricardo Luiz Dantas Machado
author_sort Wanessa Christina de Souza-Neiras
collection DOAJ
description The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
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spelling doaj.art-5b10f5f8c0a445a8b6bb8b98d6d0619f2023-09-03T09:14:17ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602007-06-011023245254The genetic diversity of Plasmodium vivax: a reviewWanessa Christina de Souza-NeirasLuciane Moreno Storti de MeloRicardo Luiz Dantas MachadoThe genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000300002malariaPlasmodium vivaxgenetic diversitymolecular markersphylogenyevolution
spellingShingle Wanessa Christina de Souza-Neiras
Luciane Moreno Storti de Melo
Ricardo Luiz Dantas Machado
The genetic diversity of Plasmodium vivax: a review
Memorias do Instituto Oswaldo Cruz
malaria
Plasmodium vivax
genetic diversity
molecular markers
phylogeny
evolution
title The genetic diversity of Plasmodium vivax: a review
title_full The genetic diversity of Plasmodium vivax: a review
title_fullStr The genetic diversity of Plasmodium vivax: a review
title_full_unstemmed The genetic diversity of Plasmodium vivax: a review
title_short The genetic diversity of Plasmodium vivax: a review
title_sort genetic diversity of plasmodium vivax a review
topic malaria
Plasmodium vivax
genetic diversity
molecular markers
phylogeny
evolution
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000300002
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