BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS
Osteoporosis affects the skeletal system and is characterized by a reduction in bone strength that predisposes one to an increased risk of fractures. In Italy, about 3.5 million women and 1 million men suffers from osteoporosis. These numbers are set to increase in the coming twenty years because th...
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| Format: | Article |
| Language: | English |
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Associazione Italiana Giovani Medici
2018-11-01
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| Series: | Euromediterranean Biomedical Journal |
| Subjects: | |
| Online Access: | http://www.embj.org/embj/2509/ |
| _version_ | 1811279660309282816 |
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| author | Dalila Scaturro |
| author_facet | Dalila Scaturro |
| author_sort | Dalila Scaturro |
| collection | DOAJ |
| description | Osteoporosis affects the skeletal system and is characterized by a reduction in bone strength that predisposes one to an increased risk of fractures. In Italy, about 3.5 million women and 1 million men suffers from osteoporosis. These numbers are set to increase in the coming twenty years because the percentage of the Italian population over 65 will increase by 25%.
The purpose of this study is to evaluate the general characteristics of a population of patients suffering from osteoporosis and the relation with comorbidity.
A single site, open-label, investigator-initiated, retrospective trial was conducted at the Bone Metabolic Disease Clinic, Department of Physical Medicine and Rehabilitation, University Hospital “P. Giaccone”, Palermo (Italy). 1500 patients of Bone Metabolic Diseases Clinic were enrolled from January 2009 and September 2017. All the patients were evaluated by Hologic Discovery QDR and subjected to a questionnaire that investigated general characteristics, life style, clinical data, osteoporosis pharmacological treatment, completed physical therapy, and Bone Densitometry results. The subjects with increased fracture risk have a high mean age, a lower BMI, report practicing less physical activity and less sun exposure. They also have a higher CIRS-comorbidity index and report previous fragility fractures more often. The study demonstrated a statistically significant association between the risk of fragility fractures, T-Score ≤-1, and comorbidity. This study could contribute to develop a protocol for primary prevention of fragility fractures in the female population affected by osteoporosis demonstrating a correlation between comorbidity and fragility fractures incidences. |
| first_indexed | 2024-04-13T00:58:45Z |
| format | Article |
| id | doaj.art-5b1369829619418b9364aab24bb2b4f6 |
| institution | Directory Open Access Journal |
| issn | 2279-7165 2279-7165 |
| language | English |
| last_indexed | 2024-04-13T00:58:45Z |
| publishDate | 2018-11-01 |
| publisher | Associazione Italiana Giovani Medici |
| record_format | Article |
| series | Euromediterranean Biomedical Journal |
| spelling | doaj.art-5b1369829619418b9364aab24bb2b4f62022-12-22T03:09:32ZengAssociazione Italiana Giovani MediciEuromediterranean Biomedical Journal2279-71652279-71652018-11-01133515515910.3269/1970-5492.2018.13.35BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORSDalila Scaturro0University of PalermoOsteoporosis affects the skeletal system and is characterized by a reduction in bone strength that predisposes one to an increased risk of fractures. In Italy, about 3.5 million women and 1 million men suffers from osteoporosis. These numbers are set to increase in the coming twenty years because the percentage of the Italian population over 65 will increase by 25%. The purpose of this study is to evaluate the general characteristics of a population of patients suffering from osteoporosis and the relation with comorbidity. A single site, open-label, investigator-initiated, retrospective trial was conducted at the Bone Metabolic Disease Clinic, Department of Physical Medicine and Rehabilitation, University Hospital “P. Giaccone”, Palermo (Italy). 1500 patients of Bone Metabolic Diseases Clinic were enrolled from January 2009 and September 2017. All the patients were evaluated by Hologic Discovery QDR and subjected to a questionnaire that investigated general characteristics, life style, clinical data, osteoporosis pharmacological treatment, completed physical therapy, and Bone Densitometry results. The subjects with increased fracture risk have a high mean age, a lower BMI, report practicing less physical activity and less sun exposure. They also have a higher CIRS-comorbidity index and report previous fragility fractures more often. The study demonstrated a statistically significant association between the risk of fragility fractures, T-Score ≤-1, and comorbidity. This study could contribute to develop a protocol for primary prevention of fragility fractures in the female population affected by osteoporosis demonstrating a correlation between comorbidity and fragility fractures incidences.http://www.embj.org/embj/2509/osteoporosisfracturesbone mineral densityT-Score |
| spellingShingle | Dalila Scaturro BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS Euromediterranean Biomedical Journal osteoporosis fractures bone mineral density T-Score |
| title | BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS |
| title_full | BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS |
| title_fullStr | BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS |
| title_full_unstemmed | BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS |
| title_short | BONE MINERAL DENSITY, FRAGILITY FRACTURES AND CLINICAL RISK FACTORS |
| title_sort | bone mineral density fragility fractures and clinical risk factors |
| topic | osteoporosis fractures bone mineral density T-Score |
| url | http://www.embj.org/embj/2509/ |
| work_keys_str_mv | AT dalilascaturro bonemineraldensityfragilityfracturesandclinicalriskfactors |