In vitro and in vivo assessment of the antioxidant potential of isoxazole derivatives

In vitro and in vivo assessment of the antioxidant potential of isoxazole derivatives

Abstract Previously developed fluorophenyl-isoxazole-carboxamides derivatives were re-synthesized and their scavenging activity against DPPH free radical and inhibitory activity against lipase and α-amylase enzymes were evaluated. The inhibition of the tested enzymes was weak while the most potent a...

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Bibliographic Details
Main Authors: Mohammed Hawash, Nidal Jaradat, Murad Abualhasan, Manar Thaher, Rawan Sawalhi, Nadeen Younes, Amani Shanaa, Mariam Nuseirat, Ahmed Mousa
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23050-x

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