Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians
Imaging of pulmonary invasive mould diseases (IMDs), which represents a cornerstone in their work-up, is mainly based on computed tomography (CT). The purpose of this review is to discuss their CT features, mainly those related to aspergillosis and mucormycosis. We will especially focus on atypical...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2023-09-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/32/169/230086.full |
| _version_ | 1827800008377761792 |
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| author | Alessio Casutt Frédéric Lamoth Olivier Lortholary John O. Prior Andrea Tonglet Oriol Manuel Anne Bergeron Catherine Beigelman-Aubry |
| author_facet | Alessio Casutt Frédéric Lamoth Olivier Lortholary John O. Prior Andrea Tonglet Oriol Manuel Anne Bergeron Catherine Beigelman-Aubry |
| author_sort | Alessio Casutt |
| collection | DOAJ |
| description | Imaging of pulmonary invasive mould diseases (IMDs), which represents a cornerstone in their work-up, is mainly based on computed tomography (CT). The purpose of this review is to discuss their CT features, mainly those related to aspergillosis and mucormycosis. We will especially focus on atypical radiological presentations that are increasingly observed among non-neutropenic emerging populations of patients at risk, such as those receiving novel anticancer therapies or those in the intensive care unit. We will also discuss the interest of other available imaging techniques, mainly positron emission tomography/CT, that may play a role in the diagnosis as well as evaluation of disease extent and follow-up. We will show that any new airway-centred abnormality or caveated lesion should evoke IMDs in mildly immunocompromised hosts. Limitations in their recognition may be due to potential underlying abnormalities that increase the complexity of interpretation of lung imaging, as well as the non-specificity of imaging features. In this way, the differentials of all morphological/metabolic aspects must be kept in mind for the optimal management of patients, as well as the benefit of evaluation of the vascular status. |
| first_indexed | 2024-03-11T20:00:24Z |
| format | Article |
| id | doaj.art-5b15906db68d4518bf29f7f05d7c7d15 |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-03-11T20:00:24Z |
| publishDate | 2023-09-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-5b15906db68d4518bf29f7f05d7c7d152023-10-04T08:29:29ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172023-09-013216910.1183/16000617.0086-20230086-2023Atypical imaging patterns during lung invasive mould diseases: lessons for cliniciansAlessio Casutt0Frédéric Lamoth1Olivier Lortholary2John O. Prior3Andrea Tonglet4Oriol Manuel5Anne Bergeron6Catherine Beigelman-Aubry7 Division of Pulmonology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland Infectious Diseases Service, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland University Paris Cité, Necker Enfants Malades University Hospital, AP-HP, IHU Imagine, Paris, France Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital (CHUV), Lausanne, Switzerland Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland Infectious Diseases Service, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland Department of Pulmonology, Geneva University Hospital, University of Geneva, Geneva, Switzerland Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland Imaging of pulmonary invasive mould diseases (IMDs), which represents a cornerstone in their work-up, is mainly based on computed tomography (CT). The purpose of this review is to discuss their CT features, mainly those related to aspergillosis and mucormycosis. We will especially focus on atypical radiological presentations that are increasingly observed among non-neutropenic emerging populations of patients at risk, such as those receiving novel anticancer therapies or those in the intensive care unit. We will also discuss the interest of other available imaging techniques, mainly positron emission tomography/CT, that may play a role in the diagnosis as well as evaluation of disease extent and follow-up. We will show that any new airway-centred abnormality or caveated lesion should evoke IMDs in mildly immunocompromised hosts. Limitations in their recognition may be due to potential underlying abnormalities that increase the complexity of interpretation of lung imaging, as well as the non-specificity of imaging features. In this way, the differentials of all morphological/metabolic aspects must be kept in mind for the optimal management of patients, as well as the benefit of evaluation of the vascular status.http://err.ersjournals.com/content/32/169/230086.full |
| spellingShingle | Alessio Casutt Frédéric Lamoth Olivier Lortholary John O. Prior Andrea Tonglet Oriol Manuel Anne Bergeron Catherine Beigelman-Aubry Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians European Respiratory Review |
| title | Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians |
| title_full | Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians |
| title_fullStr | Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians |
| title_full_unstemmed | Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians |
| title_short | Atypical imaging patterns during lung invasive mould diseases: lessons for clinicians |
| title_sort | atypical imaging patterns during lung invasive mould diseases lessons for clinicians |
| url | http://err.ersjournals.com/content/32/169/230086.full |
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