Targeting survivin in leukemia
Survivin, a member of the inhibitors of apoptosis family of proteins, is one of the most frequently upregulated transcripts in solid tumors and hematopoietic malignancies. Survivin’s importance in tumorigenesis is attributed to the fact that it has two functions: to suppress apoptosis and to regulat...
Main Authors: | Bing Z. Carter, Michael Andreeff |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-12-01
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Series: | Oncology Reviews |
Subjects: | |
Online Access: | http://www.oncologyreviews.org/index.php/or/article/view/156 |
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