The diagnosis and pathogenesis of chronic alcoholic myopathy
Peripheral neuromuscular apparatus lesion is a common complication of chronic alcohol intoxication. Alcohol-induced skeletal muscle diseaseis least studied now. A comprehensive clinical, neurophysiological, and morphological examination was made in 42 patients with chronic alcoholintoxication during...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-02-01
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| Series: | Нервно-мышечные болезни |
| Subjects: | |
| Online Access: | https://nmb.abvpress.ru/jour/article/view/47 |
| _version_ | 1797759114276765696 |
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| author | Yu. V. Kazantseva O. E. Zinovyeva B. S. Shenkman N. S. Shcheglova E. A. Lysenko |
| author_facet | Yu. V. Kazantseva O. E. Zinovyeva B. S. Shenkman N. S. Shcheglova E. A. Lysenko |
| author_sort | Yu. V. Kazantseva |
| collection | DOAJ |
| description | Peripheral neuromuscular apparatus lesion is a common complication of chronic alcohol intoxication. Alcohol-induced skeletal muscle diseaseis least studied now. A comprehensive clinical, neurophysiological, and morphological examination was made in 42 patients with chronic alcoholintoxication during this study. All the patients underwent skeletal muscle biopsy followed by muscle fiber morphometry. There was both selective type 2 muscle fiber atrophy and diffuse types 1 and 2 muscle fiber atrophic changes. The clinical manifestations of skeletal muscle disease corresponded to the degree of an atrophic process. There was impairment in the main components of protein synthesis at both intracellular and systemic regulation levels. |
| first_indexed | 2024-03-12T18:38:47Z |
| format | Article |
| id | doaj.art-5b1f8412684943c096a69d74c42359a4 |
| institution | Directory Open Access Journal |
| issn | 2222-8721 2413-0443 |
| language | Russian |
| last_indexed | 2024-03-12T18:38:47Z |
| publishDate | 2015-02-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Нервно-мышечные болезни |
| spelling | doaj.art-5b1f8412684943c096a69d74c42359a42023-08-02T07:53:08ZrusABV-pressНервно-мышечные болезни2222-87212413-04432015-02-0102353810.17650/2222-8721-2013-0-2-35-3841The diagnosis and pathogenesis of chronic alcoholic myopathyYu. V. Kazantseva0O. E. Zinovyeva1B. S. Shenkman2N. S. Shcheglova3E. A. Lysenko4Кафедра нервных болезней ГБОУ ВПО Первый МГМУ им. И.М. СеченоваКафедра нервных болезней ГБОУ ВПО Первый МГМУ им. И.М. СеченоваГНЦ РФ Институт медико-биологических проблем РАН, МоскваКафедра нервных болезней ГБОУ ВПО Первый МГМУ им. И.М. СеченоваГНЦ РФ Институт медико-биологических проблем РАН, МоскваPeripheral neuromuscular apparatus lesion is a common complication of chronic alcohol intoxication. Alcohol-induced skeletal muscle diseaseis least studied now. A comprehensive clinical, neurophysiological, and morphological examination was made in 42 patients with chronic alcoholintoxication during this study. All the patients underwent skeletal muscle biopsy followed by muscle fiber morphometry. There was both selective type 2 muscle fiber atrophy and diffuse types 1 and 2 muscle fiber atrophic changes. The clinical manifestations of skeletal muscle disease corresponded to the degree of an atrophic process. There was impairment in the main components of protein synthesis at both intracellular and systemic regulation levels.https://nmb.abvpress.ru/jour/article/view/47алкоголизммиопатиябиопсия мышцыэлектромиографиясинтез белкаинсулиноподобный фактор роста 1электрофорез белковатрофия волокон 2-го типаморфометрия мышц |
| spellingShingle | Yu. V. Kazantseva O. E. Zinovyeva B. S. Shenkman N. S. Shcheglova E. A. Lysenko The diagnosis and pathogenesis of chronic alcoholic myopathy Нервно-мышечные болезни алкоголизм миопатия биопсия мышцы электромиография синтез белка инсулиноподобный фактор роста 1 электрофорез белков атрофия волокон 2-го типа морфометрия мышц |
| title | The diagnosis and pathogenesis of chronic alcoholic myopathy |
| title_full | The diagnosis and pathogenesis of chronic alcoholic myopathy |
| title_fullStr | The diagnosis and pathogenesis of chronic alcoholic myopathy |
| title_full_unstemmed | The diagnosis and pathogenesis of chronic alcoholic myopathy |
| title_short | The diagnosis and pathogenesis of chronic alcoholic myopathy |
| title_sort | diagnosis and pathogenesis of chronic alcoholic myopathy |
| topic | алкоголизм миопатия биопсия мышцы электромиография синтез белка инсулиноподобный фактор роста 1 электрофорез белков атрофия волокон 2-го типа морфометрия мышц |
| url | https://nmb.abvpress.ru/jour/article/view/47 |
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