In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants

In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants

Abstract Background Genome-wide association studies have identified 55 genetic variants associated with colorectal cancer risk to date. However, potential causal genes and pathways regulated by these risk variants remain to be characterized. Therefore, we performed gene ontology enrichment and pathw...

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Bibliographic Details
Main Authors: Lenora W. M. Loo, Mathieu Lemire, Loïc Le Marchand
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Colorectal cancer
eQTL
Risk variant
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12864-017-3750-2

Internet

http://link.springer.com/article/10.1186/s12864-017-3750-2

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