Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report
Cerebral nocardia infections is a rare entity, which has been mainly reported in immunosuppressed patients. Currently, there are no clinical guidelines for first-line treatment. Our case refers to an older immunocompetent adult, with encephalopathy and left hemiparesis, associated with lesions compa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Spanish |
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Instituto Nacional de Salud
2021-11-01
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| Series: | Revista Peruana de Medicina Experimental y Salud Pública |
| Subjects: | |
| Online Access: | https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/7330 |
| _version_ | 1798020741217648640 |
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| author | Pamela Huamaní-Charagua Jesús Portocarrero-Nieto Gian Marco Arango-Rojas Alan Latorre Stalin Vilcarromero |
| author_facet | Pamela Huamaní-Charagua Jesús Portocarrero-Nieto Gian Marco Arango-Rojas Alan Latorre Stalin Vilcarromero |
| author_sort | Pamela Huamaní-Charagua |
| collection | DOAJ |
| description | Cerebral nocardia infections is a rare entity, which has been mainly reported in immunosuppressed patients. Currently, there are no clinical guidelines for first-line treatment. Our case refers to an older immunocompetent adult, with encephalopathy and left hemiparesis, associated with lesions compatible with multiple brain abscess and suggestive of infectious etiology. He initially received treatment for tuberculosis, bacterial abscess, and toxoplasmosis, without a favorable clinical response. An empirical treatment for nocardiosis started, by using meropenem and trimethoprim / sulfamethoxazole, and clinical and imaging improvement was achieved. The occurrence of adverse events forces the temporary use of alternative medications. We highlight some criteria for including nocardiosis in the differential diagnosis in cases of multiple brain abscess and mention laboratory diagnostic methods and drugs to initiate empirical treatment. |
| first_indexed | 2024-04-11T17:02:34Z |
| format | Article |
| id | doaj.art-5b27d67e4f414a4baad113639ea847ba |
| institution | Directory Open Access Journal |
| issn | 1726-4634 1726-4642 |
| language | Spanish |
| last_indexed | 2024-04-11T17:02:34Z |
| publishDate | 2021-11-01 |
| publisher | Instituto Nacional de Salud |
| record_format | Article |
| series | Revista Peruana de Medicina Experimental y Salud Pública |
| spelling | doaj.art-5b27d67e4f414a4baad113639ea847ba2022-12-22T04:13:07ZspaInstituto Nacional de SaludRevista Peruana de Medicina Experimental y Salud Pública1726-46341726-46422021-11-01383463610.17843/rpmesp.2021.383.73302562Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case reportPamela Huamaní-Charagua0Jesús Portocarrero-Nieto1Gian Marco Arango-Rojas2Alan Latorre3Stalin Vilcarromero4Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú. Universidad Nacional Mayor de San Marcos. Lima, Perú. Médico cirujanoHospital Nacional Edgardo Rebagliati Martins. Lima, Perú. Universidad Peruana Cayetano Heredia. Lima, Perú. Médico cirujanoHospital Nacional Edgardo Rebagliati Martins. Lima, Perú. médico infectólogoHospital Nacional Edgardo Rebagliati Martins. Lima, Perú. médico patólogoHospital Nacional Edgardo Rebagliati Martins. Lima, Perú. Universidad Peruana Cayetano Heredia. Lima, Perú. Médico cirujanoCerebral nocardia infections is a rare entity, which has been mainly reported in immunosuppressed patients. Currently, there are no clinical guidelines for first-line treatment. Our case refers to an older immunocompetent adult, with encephalopathy and left hemiparesis, associated with lesions compatible with multiple brain abscess and suggestive of infectious etiology. He initially received treatment for tuberculosis, bacterial abscess, and toxoplasmosis, without a favorable clinical response. An empirical treatment for nocardiosis started, by using meropenem and trimethoprim / sulfamethoxazole, and clinical and imaging improvement was achieved. The occurrence of adverse events forces the temporary use of alternative medications. We highlight some criteria for including nocardiosis in the differential diagnosis in cases of multiple brain abscess and mention laboratory diagnostic methods and drugs to initiate empirical treatment.https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/7330nocardiosisabscesoencéfaloinmunocompetentediagnósticoterapéutica |
| spellingShingle | Pamela Huamaní-Charagua Jesús Portocarrero-Nieto Gian Marco Arango-Rojas Alan Latorre Stalin Vilcarromero Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report Revista Peruana de Medicina Experimental y Salud Pública nocardiosis absceso encéfalo inmunocompetente diagnóstico terapéutica |
| title | Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report |
| title_full | Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report |
| title_fullStr | Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report |
| title_full_unstemmed | Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report |
| title_short | Brain abscess due to Nocardia sp. in an immunocompetent patient in Peru: a case report |
| title_sort | brain abscess due to nocardia sp in an immunocompetent patient in peru a case report |
| topic | nocardiosis absceso encéfalo inmunocompetente diagnóstico terapéutica |
| url | https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/7330 |
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