Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment

Introduction. Chronic combined periodontal and periapical lesions have a negative impact on the human organism, since they are a source of intoxication and sensitization causing progression of infection, development of focal sequelae and secondary immunodeficiency. Problem of successful treatment of...

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Main Authors: Marta Holeyko, Volodymyr Zubachyk
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2015-12-01
Series:Journal of Medical Science
Subjects:
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/2
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author Marta Holeyko
Volodymyr Zubachyk
author_facet Marta Holeyko
Volodymyr Zubachyk
author_sort Marta Holeyko
collection DOAJ
description Introduction. Chronic combined periodontal and periapical lesions have a negative impact on the human organism, since they are a source of intoxication and sensitization causing progression of infection, development of focal sequelae and secondary immunodeficiency. Problem of successful treatment of apical and marginal periodontitis is associated with a significant prevalence of these diseases, a complexity of medical procedures, a substantial proportion of failures and complications, and with a lack of long-term stability of gained results. Aim. The aim of this work was to investigate clinical effectiveness of drug formulation with thiotriazoline and chloramphenicol in the integrated treatment of combined apical and marginal periodontitis. Meterial and methods. The condition of oral cavity of the 65 patients with combined lesions of periodontal and endodontic tissues before and after treatment was studied. Outcomes measured were X-ray examination, probing depth, OHI-S, PMA, PI, SBI indices. The complex treatment has been worked out in the patients of main group and the ointment with thiotriazoline and chloramphenicol was introduced in the scheme of periodontal treatment Results and conclusions. Results of applied treatment indicated to the acceleration of healing process, reduction of exudation period and decrease of exacerbations frequency in the patients of main group. Clinical experience also demonstrated positive dynamic in changes of periodontal indices after the conducted treatment.
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spelling doaj.art-5b2aae787dde44e2a67872cb9db61f482022-12-21T20:02:34ZengPoznan University of Medical SciencesJournal of Medical Science2353-97982353-98012015-12-0184410.20883/medical.e2Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointmentMarta Holeyko0Volodymyr Zubachyk1Department of Therapeutic Dentistry, Danylo Halytsky Lviv National Medical University, Lviv, UkraineDepartment of Therapeutic Dentistry, Danylo Halytsky Lviv National Medical University, Lviv, UkraineIntroduction. Chronic combined periodontal and periapical lesions have a negative impact on the human organism, since they are a source of intoxication and sensitization causing progression of infection, development of focal sequelae and secondary immunodeficiency. Problem of successful treatment of apical and marginal periodontitis is associated with a significant prevalence of these diseases, a complexity of medical procedures, a substantial proportion of failures and complications, and with a lack of long-term stability of gained results. Aim. The aim of this work was to investigate clinical effectiveness of drug formulation with thiotriazoline and chloramphenicol in the integrated treatment of combined apical and marginal periodontitis. Meterial and methods. The condition of oral cavity of the 65 patients with combined lesions of periodontal and endodontic tissues before and after treatment was studied. Outcomes measured were X-ray examination, probing depth, OHI-S, PMA, PI, SBI indices. The complex treatment has been worked out in the patients of main group and the ointment with thiotriazoline and chloramphenicol was introduced in the scheme of periodontal treatment Results and conclusions. Results of applied treatment indicated to the acceleration of healing process, reduction of exudation period and decrease of exacerbations frequency in the patients of main group. Clinical experience also demonstrated positive dynamic in changes of periodontal indices after the conducted treatment.https://jms.ump.edu.pl/index.php/JMS/article/view/2chronic generalized periodontitisapical periodontitistreatmentointment with thiotriazoline and chloramphenicol
spellingShingle Marta Holeyko
Volodymyr Zubachyk
Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
Journal of Medical Science
chronic generalized periodontitis
apical periodontitis
treatment
ointment with thiotriazoline and chloramphenicol
title Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
title_full Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
title_fullStr Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
title_full_unstemmed Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
title_short Assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
title_sort assessment of effectiveness of complex treatment of apical and marginal periodontitis with thiotriazoline and chloramphenicol ointment
topic chronic generalized periodontitis
apical periodontitis
treatment
ointment with thiotriazoline and chloramphenicol
url https://jms.ump.edu.pl/index.php/JMS/article/view/2
work_keys_str_mv AT martaholeyko assessmentofeffectivenessofcomplextreatmentofapicalandmarginalperiodontitiswiththiotriazolineandchloramphenicolointment
AT volodymyrzubachyk assessmentofeffectivenessofcomplextreatmentofapicalandmarginalperiodontitiswiththiotriazolineandchloramphenicolointment