Pharmacological iron-chelation as an assisted nutritional immunity strategy against Piscirickettsia salmonis infection

Pharmacological iron-chelation as an assisted nutritional immunity strategy against Piscirickettsia salmonis infection

Abstract Salmonid Rickettsial Septicaemia (SRS), caused by Piscirickettsia salmonis, is a severe bacterial disease in the Chilean salmon farming industry. Vaccines and antibiotics are the current strategies to fight SRS; however, the high frequency of new epizootic events confirms the need to develo...

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Bibliographic Details
Main Authors: Mario Caruffo, Dinka Mandakovic, Madelaine Mejías, Ignacio Chávez-Báez, Pablo Salgado, Daniela Ortiz, Liliana Montt, Javiera Pérez-Valenzuela, Francisca Vera-Tamargo, José Manuel Yánez, Jurij Wacyk, Rodrigo Pulgar
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Veterinary Research
Subjects:
Piscirickettsia salmonis
host-directed therapy (HDT)
iron-chelator
deferiprone (DFP)
infection
Online Access:http://link.springer.com/article/10.1186/s13567-020-00845-2

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