The hazards of hazard identification in environmental epidemiology

Abstract Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process. Particu...

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Main Author: Rodolfo Saracci
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Environmental Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12940-017-0296-3
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author Rodolfo Saracci
author_facet Rodolfo Saracci
author_sort Rodolfo Saracci
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description Abstract Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process. Particularly relevant in this respect are components less amenable to logical or mathematical formalization and essentially dependent on scientists’ judgment. Four such potentially hazardous components that are capable of distorting the correct process of hazard identification are reviewed and discussed from an epidemiologist perspective: (1) lexical mix-up of hazard and risk (2) scientific questions as distinct from testable hypotheses, and implications for the hierarchy of strength of evidence obtainable from different types of study designs (3) assumptions in prior beliefs and model choices and (4) conflicts of interest. Four suggestions are put forward to strengthen a process that remains in several aspects judgmental, but not arbitrary, in nature.
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spelling doaj.art-5b2db29f49bd4b159eb9ff1a16e46c612022-12-22T03:33:19ZengBMCEnvironmental Health1476-069X2017-08-011611810.1186/s12940-017-0296-3The hazards of hazard identification in environmental epidemiologyRodolfo Saracci0International Agency for Research on CancerAbstract Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process. Particularly relevant in this respect are components less amenable to logical or mathematical formalization and essentially dependent on scientists’ judgment. Four such potentially hazardous components that are capable of distorting the correct process of hazard identification are reviewed and discussed from an epidemiologist perspective: (1) lexical mix-up of hazard and risk (2) scientific questions as distinct from testable hypotheses, and implications for the hierarchy of strength of evidence obtainable from different types of study designs (3) assumptions in prior beliefs and model choices and (4) conflicts of interest. Four suggestions are put forward to strengthen a process that remains in several aspects judgmental, but not arbitrary, in nature.http://link.springer.com/article/10.1186/s12940-017-0296-3Bayes’ theoremConflict of interestHazard identificationIARC MonographsLinearityModel assumptions
spellingShingle Rodolfo Saracci
The hazards of hazard identification in environmental epidemiology
Environmental Health
Bayes’ theorem
Conflict of interest
Hazard identification
IARC Monographs
Linearity
Model assumptions
title The hazards of hazard identification in environmental epidemiology
title_full The hazards of hazard identification in environmental epidemiology
title_fullStr The hazards of hazard identification in environmental epidemiology
title_full_unstemmed The hazards of hazard identification in environmental epidemiology
title_short The hazards of hazard identification in environmental epidemiology
title_sort hazards of hazard identification in environmental epidemiology
topic Bayes’ theorem
Conflict of interest
Hazard identification
IARC Monographs
Linearity
Model assumptions
url http://link.springer.com/article/10.1186/s12940-017-0296-3
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