Investigating a Library of Flavonoids as Potential Inhibitors of a Cancer Therapeutic Target MEK2 Using in Silico Methods

Investigating a Library of Flavonoids as Potential Inhibitors of a Cancer Therapeutic Target MEK2 Using in Silico Methods

The second leading cause of death in the world is cancer. Mitogen-activated protein kinase (MAPK) and extracellular signal-regulated protein kinase (ERK) 1 and 2 (MEK1/2) stand out among the different anticancer therapeutic targets. Many MEK1/2 inhibitors are approved and widely used as anticancer d...

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Bibliographic Details
Main Authors:	Wejdan M. AlZahrani, Shareefa A. AlGhamdi, Sayed S. Sohrab, Mohd Rehan
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	International Journal of Molecular Sciences
Subjects:	MAPK MEK2 flavonoids molecular docking ADMET molecular dynamics simulation
Online Access:	https://www.mdpi.com/1422-0067/24/5/4446

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