A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups

Background: Overweight and obesity is the most common co-morbidity and disease modifier of asthma; it has been associated with increased risk of asthma exacerbations, worse respiratory symptoms and poor asthma control. The objective of study was to determine the relation of body mass index (BMI) wit...

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Main Authors: Shreenivasa A, Abhinav Chaudhary, Pooja B Wagganavar, Tariq Mahmood, Vishak Acharya K
Format: Article
Language:English
Published: KIMS Foundation and Research Center 2023-07-01
Series:Journal of Medical and Scientific Research
Subjects:
Online Access:http://jmsronline.com/archive-article/Clinical-spirometric-profile-asthma-different-body-mass-index
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author Shreenivasa A
Abhinav Chaudhary
Pooja B Wagganavar
Tariq Mahmood
Vishak Acharya K
author_facet Shreenivasa A
Abhinav Chaudhary
Pooja B Wagganavar
Tariq Mahmood
Vishak Acharya K
author_sort Shreenivasa A
collection DOAJ
description Background: Overweight and obesity is the most common co-morbidity and disease modifier of asthma; it has been associated with increased risk of asthma exacerbations, worse respiratory symptoms and poor asthma control. The objective of study was to determine the relation of body mass index (BMI) with the level of asthma control and to study the clinical presentation and spirometric profile of asthma patients from different BMI groups. Materials and methods: The descriptive prospective study done among confirmed asthmatic patients who were attending the Department of Pulmonary Medicine, outpatient department (OPD) and inpatient department (IPD). The study was demographic, clinical and spirometric parameters in asthmatic patients who were on optimal pharmacotherapy among different BMI categories. Results: Total 144 diagnosed asthma patients were included; the overall mean age of the study group was 34.27 ± 11.7 years and the majority of patients 50 (34.72%) were between 18-27 years of age group. Moderate asthma (FEV1 60-79) was observed to be the most common in all BMI groups. The severe asthma (FEV1 <60) was observed with BMI > 30kg/m2 in asthma patients (p=0.27). Conclusions: The poor control of asthma was significantly frequent in the overweight and obese BMI group, regardless of the findings of no differences in spirometry. Our results suggest that obese individuals with asthma show a higher incidence of one-year follow-up hospitalization due to exacerbation symptoms than non-obese individuals.
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spelling doaj.art-5b302a56d4454891a26a96bdf8ec87fb2023-10-04T06:39:09ZengKIMS Foundation and Research CenterJournal of Medical and Scientific Research2321-13262394-112X2023-07-0111319820310.17727/JMSR.2023/11-37A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groupsShreenivasa A0Abhinav Chaudhary1Pooja B Wagganavar2Tariq Mahmood3Vishak Acharya K4Department of Pulmonary Medicine, Karwar Institute of Medical Sciences Karwar, Karnataka 581301, IndiaDepartment of Pulmonary Medicine, Apollomedics Superspeciality Hospital, Lucknow, Uttar Pradesh 226012, IndiaDepartment of Ophthalmology, Karwar Institute of Medical Sciences Karwar, Karnataka 581301, IndiaDepartment of Pulmonary Medicine, M.L.N Medical College, Allahabad, Uttarpradesh 211002, IndiaDepartment of Pulmonary Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka 575001, IndiaBackground: Overweight and obesity is the most common co-morbidity and disease modifier of asthma; it has been associated with increased risk of asthma exacerbations, worse respiratory symptoms and poor asthma control. The objective of study was to determine the relation of body mass index (BMI) with the level of asthma control and to study the clinical presentation and spirometric profile of asthma patients from different BMI groups. Materials and methods: The descriptive prospective study done among confirmed asthmatic patients who were attending the Department of Pulmonary Medicine, outpatient department (OPD) and inpatient department (IPD). The study was demographic, clinical and spirometric parameters in asthmatic patients who were on optimal pharmacotherapy among different BMI categories. Results: Total 144 diagnosed asthma patients were included; the overall mean age of the study group was 34.27 ± 11.7 years and the majority of patients 50 (34.72%) were between 18-27 years of age group. Moderate asthma (FEV1 60-79) was observed to be the most common in all BMI groups. The severe asthma (FEV1 <60) was observed with BMI > 30kg/m2 in asthma patients (p=0.27). Conclusions: The poor control of asthma was significantly frequent in the overweight and obese BMI group, regardless of the findings of no differences in spirometry. Our results suggest that obese individuals with asthma show a higher incidence of one-year follow-up hospitalization due to exacerbation symptoms than non-obese individuals.http://jmsronline.com/archive-article/Clinical-spirometric-profile-asthma-different-body-mass-indexobesityasthmaspirometryhospitalizationbody mass index
spellingShingle Shreenivasa A
Abhinav Chaudhary
Pooja B Wagganavar
Tariq Mahmood
Vishak Acharya K
A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
Journal of Medical and Scientific Research
obesity
asthma
spirometry
hospitalization
body mass index
title A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
title_full A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
title_fullStr A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
title_full_unstemmed A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
title_short A comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
title_sort comparative study to determine clinical and spirometric profile among patients of asthma in different body mass index groups
topic obesity
asthma
spirometry
hospitalization
body mass index
url http://jmsronline.com/archive-article/Clinical-spirometric-profile-asthma-different-body-mass-index
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