Interaction Dynamics Determine Signaling and Output Pathway Responses

Interaction Dynamics Determine Signaling and Output Pathway Responses

The understanding of interaction dynamics in signaling pathways can shed light on pathway architecture and provide insights into targets for intervention. Here, we explored the relevance of kinetic rate constants of a key upstream osmosensor in the yeast high-osmolarity glycerol-mitogen-activated pr...

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Bibliographic Details
Main Authors: Klement Stojanovski, Tony Ferrar, Hannah Benisty, Friedemann Uschner, Javier Delgado, Javier Jimenez, Carme Solé, Eulalia de Nadal, Edda Klipp, Francesc Posas, Luis Serrano, Christina Kiel
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Cell Reports
Subjects:
kinetic perturbations
phosphorelay
HOG-MAPK pathway
osmostress response
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717303613

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