Clinical Features of COVID-19 in Children

In early December, pneumonia cases of unknown origin started to appear and, on the 7th of January 2020, these cases were declared to be caused by a novel beta-coronavirus according to viral genome sequencing on the 11th of February, 2020. Coronaviruses are enveloped, single strand RNA viruses that h...

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Main Authors: Zümrüt Şahbudak Bal, Zafer Kurugöl, Ferda Özkınay
Format: Article
Language:English
Published: Galenos Yayinevi 2020-06-01
Series:Journal of Pediatric Research
Subjects:
Online Access: http://jpedres.org/archives/archive-detail/article-preview/clinical-features-of-covd-19-in-children/38427
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author Zümrüt Şahbudak Bal
Zafer Kurugöl
Ferda Özkınay
author_facet Zümrüt Şahbudak Bal
Zafer Kurugöl
Ferda Özkınay
author_sort Zümrüt Şahbudak Bal
collection DOAJ
description In early December, pneumonia cases of unknown origin started to appear and, on the 7th of January 2020, these cases were declared to be caused by a novel beta-coronavirus according to viral genome sequencing on the 11th of February, 2020. Coronaviruses are enveloped, single strand RNA viruses that have been known to have the ability to mutate rapidly, alter tissue tropism and adjust to different epidemiological situations. As of the end of April 2020, 122,392 laboratory-confirmed cases of COVID-19 had been detected in Turkey, of whom 3,258 died. From the beginning of the COVID-19 epidemic, children seem to be less affected than adults. Therefore, there are limited data regarding the clinical features of COVID-19 in children. The majority of children with confirmed COVID-19 had a history of household contact. The most common symptoms were fever and cough. Previous data suggest that nearly half of patients are afebrile at the onset of the disease. Hospitalization and PICU admission rates for children were lower than for adults. However, PICU admission can be necessitated in children with severe disease. Infants, particularly under the age of 12 months, were more likely to develop severe disease. In children, milder and asymptomatic cases can be challenging and can play a role in transmission. In particular, clinicians should test those children who have a history of family cluster even though they are asymptomatic or present with mild symptoms.
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spelling doaj.art-5b33c27fefc24e41a11c8401291127e32023-02-15T16:20:31ZengGalenos YayineviJournal of Pediatric Research2147-94452587-24782020-06-0172889110.4274/jpr.galenos.2020.6043713049054Clinical Features of COVID-19 in ChildrenZümrüt Şahbudak Bal0Zafer Kurugöl1Ferda Özkınay2 Ege University Faculty of Medicine, Department of Pediatrics, İzmir, Turkey Ege University Faculty of Medicine, Department of Pediatrics, İzmir, Turkey Ege University Faculty of Medicine, Department of Pediatrics, İzmir, Turkey In early December, pneumonia cases of unknown origin started to appear and, on the 7th of January 2020, these cases were declared to be caused by a novel beta-coronavirus according to viral genome sequencing on the 11th of February, 2020. Coronaviruses are enveloped, single strand RNA viruses that have been known to have the ability to mutate rapidly, alter tissue tropism and adjust to different epidemiological situations. As of the end of April 2020, 122,392 laboratory-confirmed cases of COVID-19 had been detected in Turkey, of whom 3,258 died. From the beginning of the COVID-19 epidemic, children seem to be less affected than adults. Therefore, there are limited data regarding the clinical features of COVID-19 in children. The majority of children with confirmed COVID-19 had a history of household contact. The most common symptoms were fever and cough. Previous data suggest that nearly half of patients are afebrile at the onset of the disease. Hospitalization and PICU admission rates for children were lower than for adults. However, PICU admission can be necessitated in children with severe disease. Infants, particularly under the age of 12 months, were more likely to develop severe disease. In children, milder and asymptomatic cases can be challenging and can play a role in transmission. In particular, clinicians should test those children who have a history of family cluster even though they are asymptomatic or present with mild symptoms. http://jpedres.org/archives/archive-detail/article-preview/clinical-features-of-covd-19-in-children/38427 covid-19sars-cov-2childclinical feature
spellingShingle Zümrüt Şahbudak Bal
Zafer Kurugöl
Ferda Özkınay
Clinical Features of COVID-19 in Children
Journal of Pediatric Research
covid-19
sars-cov-2
child
clinical feature
title Clinical Features of COVID-19 in Children
title_full Clinical Features of COVID-19 in Children
title_fullStr Clinical Features of COVID-19 in Children
title_full_unstemmed Clinical Features of COVID-19 in Children
title_short Clinical Features of COVID-19 in Children
title_sort clinical features of covid 19 in children
topic covid-19
sars-cov-2
child
clinical feature
url http://jpedres.org/archives/archive-detail/article-preview/clinical-features-of-covd-19-in-children/38427
work_keys_str_mv AT zumrutsahbudakbal clinicalfeaturesofcovid19inchildren
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AT ferdaozkınay clinicalfeaturesofcovid19inchildren