New insights into balancing wound healing and scarless skin repair

Scars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various...

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Main Authors: Shengxi Zhou, Mengbo Xie, Jingjing Su, Bingjie Cai, Jingan Li, Kun Zhang
Format: Article
Language:English
Published: SAGE Publishing 2023-07-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231185848
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author Shengxi Zhou
Mengbo Xie
Jingjing Su
Bingjie Cai
Jingan Li
Kun Zhang
author_facet Shengxi Zhou
Mengbo Xie
Jingjing Su
Bingjie Cai
Jingan Li
Kun Zhang
author_sort Shengxi Zhou
collection DOAJ
description Scars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various cells, cytokines and mechanical force interact, is critical to developing a treatment that can achieve scarless wound healing. Therefore, this paper reviews the types of wounds, the mechanism of scar formation in the healing process, and the current research progress on the dual consideration of wound healing and scar prevention, and some strategies for the treatment of scar free wound repair.
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spelling doaj.art-5b389a7a5ed147adbba486327d3069d12023-07-27T17:03:25ZengSAGE PublishingJournal of Tissue Engineering2041-73142023-07-011410.1177/20417314231185848New insights into balancing wound healing and scarless skin repairShengxi Zhou0Mengbo Xie1Jingjing Su2Bingjie Cai3Jingan Li4Kun Zhang5School of Life Science, Zhengzhou University, Zhengzhou, Henan, P. R. ChinaSchool of Life Science, Zhengzhou University, Zhengzhou, Henan, P. R. ChinaSchool of Life Science, Zhengzhou University, Zhengzhou, Henan, P. R. ChinaDepartment of Dermatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. ChinaSchool of Materials Science and Engineering, Zhengzhou University, Zhengzhou, Henan, P. R. ChinaSchool of Life Science, Zhengzhou University, Zhengzhou, Henan, P. R. ChinaScars caused by skin injuries after burns, wounds, abrasions and operations have serious physical and psychological effects on patients. In recent years, the research of scar free wound repair has been greatly expanded. However, understanding the complex mechanisms of wound healing, in which various cells, cytokines and mechanical force interact, is critical to developing a treatment that can achieve scarless wound healing. Therefore, this paper reviews the types of wounds, the mechanism of scar formation in the healing process, and the current research progress on the dual consideration of wound healing and scar prevention, and some strategies for the treatment of scar free wound repair.https://doi.org/10.1177/20417314231185848
spellingShingle Shengxi Zhou
Mengbo Xie
Jingjing Su
Bingjie Cai
Jingan Li
Kun Zhang
New insights into balancing wound healing and scarless skin repair
Journal of Tissue Engineering
title New insights into balancing wound healing and scarless skin repair
title_full New insights into balancing wound healing and scarless skin repair
title_fullStr New insights into balancing wound healing and scarless skin repair
title_full_unstemmed New insights into balancing wound healing and scarless skin repair
title_short New insights into balancing wound healing and scarless skin repair
title_sort new insights into balancing wound healing and scarless skin repair
url https://doi.org/10.1177/20417314231185848
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AT bingjiecai newinsightsintobalancingwoundhealingandscarlessskinrepair
AT jinganli newinsightsintobalancingwoundhealingandscarlessskinrepair
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