<i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites
Secondary phenolic metabolites are defined as valuable natural products synthesized by different organisms that are not essential for growth and development. These compounds play an essential role in plant defense mechanisms and an important role in the pharmaceutical, cosmetics, food, and agricultu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/19/7343 |
| _version_ | 1797551767525785600 |
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| author | Grzegorz Chrzanowski |
| author_facet | Grzegorz Chrzanowski |
| author_sort | Grzegorz Chrzanowski |
| collection | DOAJ |
| description | Secondary phenolic metabolites are defined as valuable natural products synthesized by different organisms that are not essential for growth and development. These compounds play an essential role in plant defense mechanisms and an important role in the pharmaceutical, cosmetics, food, and agricultural industries. Despite the vast chemical diversity of natural compounds, their content in plants is very low, and, as a consequence, this eliminates the possibility of the production of these interesting secondary metabolites from plants. Therefore, microorganisms are widely used as cell factories by industrial biotechnology, in the production of different non-native compounds. Among microorganisms commonly used in biotechnological applications, yeast are a prominent host for the diverse secondary metabolite biosynthetic pathways. <i>Saccharomyces cerevisiae</i> is often regarded as a better host organism for the heterologous production of phenolic compounds, particularly if the expression of different plant genes is necessary. |
| first_indexed | 2024-03-10T15:50:39Z |
| format | Article |
| id | doaj.art-5b3ab039851a4790adf9c2714b0c11e4 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T15:50:39Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-5b3ab039851a4790adf9c2714b0c11e42023-11-20T16:05:37ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-10-012119734310.3390/ijms21197343<i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic MetabolitesGrzegorz Chrzanowski0Department of Biotechnology, Institute of Biology and Biotechnology, University of Rzeszow, 35-310 Rzeszow, PolandSecondary phenolic metabolites are defined as valuable natural products synthesized by different organisms that are not essential for growth and development. These compounds play an essential role in plant defense mechanisms and an important role in the pharmaceutical, cosmetics, food, and agricultural industries. Despite the vast chemical diversity of natural compounds, their content in plants is very low, and, as a consequence, this eliminates the possibility of the production of these interesting secondary metabolites from plants. Therefore, microorganisms are widely used as cell factories by industrial biotechnology, in the production of different non-native compounds. Among microorganisms commonly used in biotechnological applications, yeast are a prominent host for the diverse secondary metabolite biosynthetic pathways. <i>Saccharomyces cerevisiae</i> is often regarded as a better host organism for the heterologous production of phenolic compounds, particularly if the expression of different plant genes is necessary.https://www.mdpi.com/1422-0067/21/19/7343heterologous productionshikimic acid pathwayphenolic acidsflavonoidsanthocyaninsstilbenes |
| spellingShingle | Grzegorz Chrzanowski <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites International Journal of Molecular Sciences heterologous production shikimic acid pathway phenolic acids flavonoids anthocyanins stilbenes |
| title | <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites |
| title_full | <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites |
| title_fullStr | <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites |
| title_full_unstemmed | <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites |
| title_short | <i>Saccharomyces Cerevisiae</i>—An Interesting Producer of Bioactive Plant Polyphenolic Metabolites |
| title_sort | i saccharomyces cerevisiae i an interesting producer of bioactive plant polyphenolic metabolites |
| topic | heterologous production shikimic acid pathway phenolic acids flavonoids anthocyanins stilbenes |
| url | https://www.mdpi.com/1422-0067/21/19/7343 |
| work_keys_str_mv | AT grzegorzchrzanowski isaccharomycescerevisiaeianinterestingproducerofbioactiveplantpolyphenolicmetabolites |