Alkaloids from Veratrum taliense Exert Cardiovascular Toxic Effects via Cardiac Sodium Channel Subtype 1.5

Alkaloids from Veratrum taliense Exert Cardiovascular Toxic Effects via Cardiac Sodium Channel Subtype 1.5

Several species of the genus Veratrum that produce steroid alkaloids are commonly used to treat pain and hypertension in China and Europe. However, Veratrum alkaloids (VAs) induce serious cardiovascular toxicity. In China, Veratrum treatment often leads to many side effects and even causes the death...

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Bibliographic Details
Main Authors: Gan Wang, Ming-Qiang Rong, Qiong Li, Ya-Ping Liu, Cheng-Bo Long, Ping Meng, Hui-Ming Yao, Ren Lai, Xiao-Dong Luo
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Toxins
Subjects:
Veratrum taliense
NaV1.5
cardiovascular toxicity
Online Access:http://www.mdpi.com/2072-6651/8/1/12

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