Role of Natural Autoantibodies (NAA) and Natural IgM Anti-leucocyte autoantibodies (IgM-ALA) in Health and Disease

Role of Natural Autoantibodies (NAA) and Natural IgM Anti-leucocyte autoantibodies (IgM-ALA) in Health and Disease

We review how polyreactive natural IgM autoantibodies (IgM-NAA) protect the host from invading micro-organisms and host neo-antigens that are constantly being produced by oxidation mechanisms and cell apoptosis. Secondly, we discuss how IgM-NAA and IgM-ALA inhibits auto-immune inflammation by anti-...

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Bibliographic Details
Main Author:	Peter Isaac Lobo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-06-01
Series:	Frontiers in Immunology
Subjects:	allograft rejection natural antibodies SLE nephritis Renal IRI Natural IgM autoantibodies pathogenic IgG autoantibodies
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00198/full

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