Laser Treatment Monitoring with Reflectance Confocal Microscopy
Laser treatments have become popular in Dermatology. In parallel to technologic development enabling the availability of different laser wavelengths, non-invasive skin imaging techniques, such as reflectance confocal microscopy (RCM), have been used to explore morphologic and qualitative skin charac...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
|
| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1648-9144/59/6/1039 |
| _version_ | 1797593579257856000 |
|---|---|
| author | Stefania Guida Caterina Longo Simone Amato Anthony M. Rossi Marco Manfredini Silvana Ciardo Marco Spadafora Steven P. Nisticò Santo R. Mercuri Franco Rongioletti Nicola Zerbinati Giovanni Pellacani |
| author_facet | Stefania Guida Caterina Longo Simone Amato Anthony M. Rossi Marco Manfredini Silvana Ciardo Marco Spadafora Steven P. Nisticò Santo R. Mercuri Franco Rongioletti Nicola Zerbinati Giovanni Pellacani |
| author_sort | Stefania Guida |
| collection | DOAJ |
| description | Laser treatments have become popular in Dermatology. In parallel to technologic development enabling the availability of different laser wavelengths, non-invasive skin imaging techniques, such as reflectance confocal microscopy (RCM), have been used to explore morphologic and qualitative skin characteristics. Specifically, RCM can be applied to cosmetically sensitive skin areas such as the face, without the need for skin biopsies. For these reasons, apart from its current use in skin cancer diagnosis, our systematic review reveals how RCM can be employed in the field of laser treatment monitoring, being particularly suitable for the evaluation of variations in epidermis and dermis, and pigmentary and vascular characteristics of the skin. This systematic review article aims to provide an overview on current applications of RCM laser treatment monitoring, while describing RCM features identified for different applications. Studies on human subjects treated with laser treatments, monitored with RCM, were included in the current systematic review. Five groups of treatments were identified and described: skin rejuvenation, scar tissue, pigmentary disorders, vascular disorders and other. Interestingly, RCM can assist treatments with lasers targeting all chromophores in the skin and exploiting laser induced optical breakdown. Treatment monitoring encompasses assessment at baseline and examination of changes after treatment, therefore revealing details in morphologic alterations underlying different skin conditions and mechanisms of actions of laser therapy, as well as objectify results after treatment. |
| first_indexed | 2024-03-11T02:11:17Z |
| format | Article |
| id | doaj.art-5b44f09fcf53442887628a0a876c0905 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T02:11:17Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-5b44f09fcf53442887628a0a876c09052023-11-18T11:30:36ZengMDPI AGMedicina1010-660X1648-91442023-05-01596103910.3390/medicina59061039Laser Treatment Monitoring with Reflectance Confocal MicroscopyStefania Guida0Caterina Longo1Simone Amato2Anthony M. Rossi3Marco Manfredini4Silvana Ciardo5Marco Spadafora6Steven P. Nisticò7Santo R. Mercuri8Franco Rongioletti9Nicola Zerbinati10Giovanni Pellacani11School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, ItalyCentro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale—IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, ItalyDepartment of Medicine, Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USADepartment of Dermatology, University of Modena and Reggio Emilia, 41124 Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, 41124 Modena, ItalyCentro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale—IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, ItalySchool of Medicine, Vita-Salute San Raffaele University, 20132 Milan, ItalySchool of Medicine, Vita-Salute San Raffaele University, 20132 Milan, ItalyDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, ItalyDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, ItalyLaser treatments have become popular in Dermatology. In parallel to technologic development enabling the availability of different laser wavelengths, non-invasive skin imaging techniques, such as reflectance confocal microscopy (RCM), have been used to explore morphologic and qualitative skin characteristics. Specifically, RCM can be applied to cosmetically sensitive skin areas such as the face, without the need for skin biopsies. For these reasons, apart from its current use in skin cancer diagnosis, our systematic review reveals how RCM can be employed in the field of laser treatment monitoring, being particularly suitable for the evaluation of variations in epidermis and dermis, and pigmentary and vascular characteristics of the skin. This systematic review article aims to provide an overview on current applications of RCM laser treatment monitoring, while describing RCM features identified for different applications. Studies on human subjects treated with laser treatments, monitored with RCM, were included in the current systematic review. Five groups of treatments were identified and described: skin rejuvenation, scar tissue, pigmentary disorders, vascular disorders and other. Interestingly, RCM can assist treatments with lasers targeting all chromophores in the skin and exploiting laser induced optical breakdown. Treatment monitoring encompasses assessment at baseline and examination of changes after treatment, therefore revealing details in morphologic alterations underlying different skin conditions and mechanisms of actions of laser therapy, as well as objectify results after treatment.https://www.mdpi.com/1648-9144/59/6/1039laserreflectance confocal microscopylaser monitoringrejuvenationscarpigmentation |
| spellingShingle | Stefania Guida Caterina Longo Simone Amato Anthony M. Rossi Marco Manfredini Silvana Ciardo Marco Spadafora Steven P. Nisticò Santo R. Mercuri Franco Rongioletti Nicola Zerbinati Giovanni Pellacani Laser Treatment Monitoring with Reflectance Confocal Microscopy Medicina laser reflectance confocal microscopy laser monitoring rejuvenation scar pigmentation |
| title | Laser Treatment Monitoring with Reflectance Confocal Microscopy |
| title_full | Laser Treatment Monitoring with Reflectance Confocal Microscopy |
| title_fullStr | Laser Treatment Monitoring with Reflectance Confocal Microscopy |
| title_full_unstemmed | Laser Treatment Monitoring with Reflectance Confocal Microscopy |
| title_short | Laser Treatment Monitoring with Reflectance Confocal Microscopy |
| title_sort | laser treatment monitoring with reflectance confocal microscopy |
| topic | laser reflectance confocal microscopy laser monitoring rejuvenation scar pigmentation |
| url | https://www.mdpi.com/1648-9144/59/6/1039 |
| work_keys_str_mv | AT stefaniaguida lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT caterinalongo lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT simoneamato lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT anthonymrossi lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT marcomanfredini lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT silvanaciardo lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT marcospadafora lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT stevenpnistico lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT santormercuri lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT francorongioletti lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT nicolazerbinati lasertreatmentmonitoringwithreflectanceconfocalmicroscopy AT giovannipellacani lasertreatmentmonitoringwithreflectanceconfocalmicroscopy |