Spontaneous Myocarditis in Mice Predisposed to Autoimmune Disease: Including Vaccination-Induced Onset

Spontaneous Myocarditis in Mice Predisposed to Autoimmune Disease: Including Vaccination-Induced Onset

Nonobese diabetic (NOD)/ShiLtJ mice, such as biobreeding rats, are used as an animal model for type 1 diabetes. Diabetes develops in NOD mice as a result of insulitis, a leukocytic infiltrate of the pancreatic islets. The onset of diabetes is associated with moderate glycosuria and nonfasting hyperg...

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Bibliographic Details
Main Authors: Takuma Hayashi, Motoki Ichikawa, Ikuo Konishi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomedicines
Subjects:
myocarditis
NF-κB1
vaccine
nonobese diabetic (NOD)
autoimmune disease
Online Access:https://www.mdpi.com/2227-9059/10/6/1443

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