Scramblases as Regulators of Proteolytic <i>ADAM</i> Function

Scramblases as Regulators of Proteolytic <i>ADAM</i> Function

Proteolytic ectodomain release is a key mechanism for regulating the function of many cell surface proteins. The sheddases <i>ADAM10</i> and <i>ADAM17</i> are the best-characterized members of the family of transmembrane disintegrin-like metalloproteinase. Constitutive proteo...

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Bibliographic Details
Main Authors: Karina Reiss, Sinje Leitzke, Jana Seidel, Maria Sperrhacke, Sucharit Bhakdi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
<i>ADAM17</i>
<i>ADAM10</i>
activation
cell membrane asymmetry
phosphatidylserine
scramblases
Online Access:https://www.mdpi.com/2077-0375/12/2/185

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