Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

The standard treatment for chronic obstructive pulmonary disease is a combination of anti-inflammatory drugs and bronchodilators. We recently found that mepenzolate bromide (MP), an antagonist for human muscarinic M3 receptor (hM3R), has both anti-inflammatory and short-acting bronchodilatory activi...

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Podrobná bibliografie
Hlavní autoři: Ken-Ichiro Tanaka, Naoki Yamakawa, Yasunobu Yamashita, Teita Asano, Yuki Kanda, Ayaka Takafuji, Masahiro Kawahara, Mitsuko Takenaga, Yoshifumi Fukunishi, Tohru Mizushima
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2018-04-01
Edice:Frontiers in Pharmacology
Témata:
chronic obstructive pulmonary disease
anti-inflammatory
long-acting bronchodilatory activity
mepenzolate
On-line přístup:http://journal.frontiersin.org/article/10.3389/fphar.2018.00344/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00344/full

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