Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.

<h4>Purpose</h4>To assess and compare safety and effectiveness between 23-gauge and 25-gauge vitrectomy systems for the treatment of common vitreoretinal diseases in non-vitrectomized eyes.<h4>Methods</h4>Retrospective evaluation of patients who underwent pars plana vitrectom...

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Main Authors: Aleksandra Sedova, Irene Steiner, Rene Peter Matzenberger, Michael Georgopoulos, Christoph Scholda, Katharina Franziska Kriechbaum, Claudette Abela-Formanek, Georgios Mylonas, Stefan Sacu, Ursula Schmidt-Erfurth, Andreas Pollreisz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248164
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author Aleksandra Sedova
Irene Steiner
Rene Peter Matzenberger
Michael Georgopoulos
Christoph Scholda
Katharina Franziska Kriechbaum
Claudette Abela-Formanek
Georgios Mylonas
Stefan Sacu
Ursula Schmidt-Erfurth
Andreas Pollreisz
author_facet Aleksandra Sedova
Irene Steiner
Rene Peter Matzenberger
Michael Georgopoulos
Christoph Scholda
Katharina Franziska Kriechbaum
Claudette Abela-Formanek
Georgios Mylonas
Stefan Sacu
Ursula Schmidt-Erfurth
Andreas Pollreisz
author_sort Aleksandra Sedova
collection DOAJ
description <h4>Purpose</h4>To assess and compare safety and effectiveness between 23-gauge and 25-gauge vitrectomy systems for the treatment of common vitreoretinal diseases in non-vitrectomized eyes.<h4>Methods</h4>Retrospective evaluation of patients who underwent pars plana vitrectomy from April 2018 to December 2019 at the Department of Ophthalmology and Optometry at the Medical University of Vienna (MUV) for the following indications: macular epiretinal membrane, macular hole, macular lamellar hole, vitreous hemorrhage, vitreous opacities, vitreomacular traction syndrome and macular edema.<h4>Results</h4>201 eyes of 195 patients that underwent 23-gauge (n = 105 eyes) or 25-gauge (n = 96 eyes) vitrectomy were included in this study. The mean best-corrected visual acuity (BCVA) improved at 1-3 months postoperatively and beyond 3 months in both gauge groups. Risk of any complication within 1 month postoperatively was lower in the 25-gauge group, but the difference was statistically not significant (HR [95% CI]: 0.95 [0.53; 1.70], p = 0.85). Intraocular pressure less than 5 mmHg was observed in 2 eyes (2%) in the 23-gauge group at the first postoperative day. Intraocular pressure elevation over 25 mmHg occurred in 5 eyes (2 eyes, 2%, in 23-gauge and 3 eyes, 3%, in 25-gauge group) at postoperative day 1, between 7 and 28 days in 5 cases (2 eyes, 2%, in 23-gauge and 3 eyes, 3%, in 25-gauge group), and in 2 eyes (2%) of the 23-gauge group at postoperative day 145 and 61, respectively. Retinal detachment occurred in 1 eye (1%) in the 23-gauge and in 3 eyes (3%) in the 25-gauge group. We did not observe any cases of endophthalmitis.<h4>Conclusion</h4>Results in terms of safety, surgical success and visual outcomes for the treatment of common vitreoretinal surgery indications seem to be comparable between 23-gauge and 25-gauge vitrectomy systems, indicating that the two gauge systems can be used equally in the clinical routine.
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spelling doaj.art-5b559ecc5d864a65bff026da581e4adf2022-12-21T18:24:33ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024816410.1371/journal.pone.0248164Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.Aleksandra SedovaIrene SteinerRene Peter MatzenbergerMichael GeorgopoulosChristoph ScholdaKatharina Franziska KriechbaumClaudette Abela-FormanekGeorgios MylonasStefan SacuUrsula Schmidt-ErfurthAndreas Pollreisz<h4>Purpose</h4>To assess and compare safety and effectiveness between 23-gauge and 25-gauge vitrectomy systems for the treatment of common vitreoretinal diseases in non-vitrectomized eyes.<h4>Methods</h4>Retrospective evaluation of patients who underwent pars plana vitrectomy from April 2018 to December 2019 at the Department of Ophthalmology and Optometry at the Medical University of Vienna (MUV) for the following indications: macular epiretinal membrane, macular hole, macular lamellar hole, vitreous hemorrhage, vitreous opacities, vitreomacular traction syndrome and macular edema.<h4>Results</h4>201 eyes of 195 patients that underwent 23-gauge (n = 105 eyes) or 25-gauge (n = 96 eyes) vitrectomy were included in this study. The mean best-corrected visual acuity (BCVA) improved at 1-3 months postoperatively and beyond 3 months in both gauge groups. Risk of any complication within 1 month postoperatively was lower in the 25-gauge group, but the difference was statistically not significant (HR [95% CI]: 0.95 [0.53; 1.70], p = 0.85). Intraocular pressure less than 5 mmHg was observed in 2 eyes (2%) in the 23-gauge group at the first postoperative day. Intraocular pressure elevation over 25 mmHg occurred in 5 eyes (2 eyes, 2%, in 23-gauge and 3 eyes, 3%, in 25-gauge group) at postoperative day 1, between 7 and 28 days in 5 cases (2 eyes, 2%, in 23-gauge and 3 eyes, 3%, in 25-gauge group), and in 2 eyes (2%) of the 23-gauge group at postoperative day 145 and 61, respectively. Retinal detachment occurred in 1 eye (1%) in the 23-gauge and in 3 eyes (3%) in the 25-gauge group. We did not observe any cases of endophthalmitis.<h4>Conclusion</h4>Results in terms of safety, surgical success and visual outcomes for the treatment of common vitreoretinal surgery indications seem to be comparable between 23-gauge and 25-gauge vitrectomy systems, indicating that the two gauge systems can be used equally in the clinical routine.https://doi.org/10.1371/journal.pone.0248164
spellingShingle Aleksandra Sedova
Irene Steiner
Rene Peter Matzenberger
Michael Georgopoulos
Christoph Scholda
Katharina Franziska Kriechbaum
Claudette Abela-Formanek
Georgios Mylonas
Stefan Sacu
Ursula Schmidt-Erfurth
Andreas Pollreisz
Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
PLoS ONE
title Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
title_full Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
title_fullStr Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
title_full_unstemmed Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
title_short Comparison of safety and effectiveness between 23-gauge and 25-gauge vitrectomy surgery in common vitreoretinal diseases.
title_sort comparison of safety and effectiveness between 23 gauge and 25 gauge vitrectomy surgery in common vitreoretinal diseases
url https://doi.org/10.1371/journal.pone.0248164
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