Diagnostics procedures in rabies

Rabies is a major zoonosis for which diagnostic techniques can only be performed in the laboratory. Laboratory techniques are preferably oriented on tissue removed from the cranium: hippocampus (Ammon's horn), cerebellum and the medulla oblongata or tissue liquids. Clinical observation may only...

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Main Authors: Malovrh Tadej, Hostnik Peter
Format: Article
Language:English
Published: Faculty of Veterinary Medicine, Belgrade 2005-01-01
Series:Veterinarski Glasnik
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0350-2457/2005/0350-24570502099M.pdf
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author Malovrh Tadej
Hostnik Peter
author_facet Malovrh Tadej
Hostnik Peter
author_sort Malovrh Tadej
collection DOAJ
description Rabies is a major zoonosis for which diagnostic techniques can only be performed in the laboratory. Laboratory techniques are preferably oriented on tissue removed from the cranium: hippocampus (Ammon's horn), cerebellum and the medulla oblongata or tissue liquids. Clinical observation may only lead to a suspicion of rabies. The only way to perform a reliable diagnosis of the disease is to identify the virus or some of its specific components using laboratory tests such as histological identification of characteristic cell lesions, immunochemical identification of rabies virus antigen and virus isolation. Serological tests are rarely used in epidemiological surveys but much more frequently in control of the vaccination programs (e.g. oral vaccination). Most commonly used serological tests are the virus neutralization test on cell culture (FAVN), virus neutralization in mice and ELISA.
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spelling doaj.art-5b56fef66e61482487df31f972a3556d2022-12-21T19:23:20ZengFaculty of Veterinary Medicine, BelgradeVeterinarski Glasnik0350-24572406-07712005-01-01591-29910510.2298/VETGL0502099M0350-24570502099MDiagnostics procedures in rabiesMalovrh Tadej0Hostnik Peter1Institute of Microbiology and Parasitology, Veterinary faculty, LjubljanaInstitute of Microbiology and Parasitology, Veterinary faculty, LjubljanaRabies is a major zoonosis for which diagnostic techniques can only be performed in the laboratory. Laboratory techniques are preferably oriented on tissue removed from the cranium: hippocampus (Ammon's horn), cerebellum and the medulla oblongata or tissue liquids. Clinical observation may only lead to a suspicion of rabies. The only way to perform a reliable diagnosis of the disease is to identify the virus or some of its specific components using laboratory tests such as histological identification of characteristic cell lesions, immunochemical identification of rabies virus antigen and virus isolation. Serological tests are rarely used in epidemiological surveys but much more frequently in control of the vaccination programs (e.g. oral vaccination). Most commonly used serological tests are the virus neutralization test on cell culture (FAVN), virus neutralization in mice and ELISA.http://www.doiserbia.nb.rs/img/doi/0350-2457/2005/0350-24570502099M.pdfrabiesdiagnostics procedures
spellingShingle Malovrh Tadej
Hostnik Peter
Diagnostics procedures in rabies
Veterinarski Glasnik
rabies
diagnostics procedures
title Diagnostics procedures in rabies
title_full Diagnostics procedures in rabies
title_fullStr Diagnostics procedures in rabies
title_full_unstemmed Diagnostics procedures in rabies
title_short Diagnostics procedures in rabies
title_sort diagnostics procedures in rabies
topic rabies
diagnostics procedures
url http://www.doiserbia.nb.rs/img/doi/0350-2457/2005/0350-24570502099M.pdf
work_keys_str_mv AT malovrhtadej diagnosticsproceduresinrabies
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