Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals

Rs4862705 in the melatonin receptor 1A gene is associated with renal function decline in type 1 diabetes individuals

AimThe pathogenesis of chronic diabetes complications has oxidative stress as one of the major elements, and single-nucleotide polymorphisms (SNPs) in genes belonging to antioxidant pathways modulate susceptibility to these complications. Considering that melatonin is a powerful antioxidant compound...

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Bibliographic Details
Main Authors: Gustavo Daher, Daniele Pereira Santos-Bezerra, Ana Mercedes Cavaleiro, Tatiana Souza Pelaes, Sharon Nina Admoni, Ricardo Vessoni Perez, Cleide Guimarães Machado, Fernanda Gaspar do Amaral, José Cipolla-Neto, Maria Lúcia Correa-Giannella
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Endocrinology
Subjects:
type 1 diabetes mellitus
diabetes-related complications
diabetic kidney disease
antioxidant activity
melatonin receptors
genetic polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1331012/full

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https://www.frontiersin.org/articles/10.3389/fendo.2024.1331012/full

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