PINK1 regulated mitophagy is evident in skeletal muscles
ABSTRACTPINK1, mutated in familial forms of Parkinson’s disease, initiates mitophagy following mitochondrial depolarization. However, it is difficult to monitor this pathway physiologically in mice as loss of PINK1 does not alter basal mitophagy levels in most tissues. To further characterize this p...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Autophagy Reports |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/27694127.2024.2326402 |