Sequential orbital apex syndrome following the COVID-19 vaccination: A case report
Background: Many kinds of vaccines have been developed worldwide to bring the coronavirus disease 2019 (COVID-19) to an end. We report a case of recurrent orbital apex syndrome following the first and third doses of SARS-CoV-2 vaccination. Case presentation: A 71-year-old woman presented with acute...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | eNeurologicalSci |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650223000059 |
| _version_ | 1797894936278859776 |
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| author | Seo-Young Choi Jae-Hwan Choi Eun Hye Oh Kwang-Dong Choi |
| author_facet | Seo-Young Choi Jae-Hwan Choi Eun Hye Oh Kwang-Dong Choi |
| author_sort | Seo-Young Choi |
| collection | DOAJ |
| description | Background: Many kinds of vaccines have been developed worldwide to bring the coronavirus disease 2019 (COVID-19) to an end. We report a case of recurrent orbital apex syndrome following the first and third doses of SARS-CoV-2 vaccination. Case presentation: A 71-year-old woman presented with acute painless diplopia and visual disturbance for two days. She had received the first dose of the COVID-19 vaccine two weeks before. She showed decreased visual acuity and ophthalmoplegia in the right eye. An orbital magnetic resonance image (MRI) revealed a hyperintense lesion with enhanced bulging in the right cavernous sinus. Following the steroid pulse therapy, she fully recovered. However, six months after the first attack, painful ophthalmoplegia with decreased visual acuity recurred in her left eye after the booster vaccination for COVID-19. MRI also showed a well-enhanced hyperintense lesion in the left orbital apex. Fortunately, her visual acuity and ocular motility returned to normal after the steroid therapy. Conclusions: Immunologic reactions from COVID-19 vaccines may cause multiple cranial neuropathies. Diverse individual immunologic states should be considered before any kind of vaccine. |
| first_indexed | 2024-04-10T07:17:16Z |
| format | Article |
| id | doaj.art-5b59e29df34f447ba2cd0c25b8fa5550 |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-04-10T07:17:16Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-5b59e29df34f447ba2cd0c25b8fa55502023-02-25T04:09:53ZengElseviereNeurologicalSci2405-65022023-03-0130100447Sequential orbital apex syndrome following the COVID-19 vaccination: A case reportSeo-Young Choi0Jae-Hwan Choi1Eun Hye Oh2Kwang-Dong Choi3Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of Korea; Corresponding author at: Department of Neurology, Pusan National University Hospital, 179, Gudeok-ro, Seo-gu, Busan, 602-739, Republic of Korea.Department of Neurology, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Republic of KoreaDepartment of Neurology, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Republic of KoreaDepartment of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of KoreaBackground: Many kinds of vaccines have been developed worldwide to bring the coronavirus disease 2019 (COVID-19) to an end. We report a case of recurrent orbital apex syndrome following the first and third doses of SARS-CoV-2 vaccination. Case presentation: A 71-year-old woman presented with acute painless diplopia and visual disturbance for two days. She had received the first dose of the COVID-19 vaccine two weeks before. She showed decreased visual acuity and ophthalmoplegia in the right eye. An orbital magnetic resonance image (MRI) revealed a hyperintense lesion with enhanced bulging in the right cavernous sinus. Following the steroid pulse therapy, she fully recovered. However, six months after the first attack, painful ophthalmoplegia with decreased visual acuity recurred in her left eye after the booster vaccination for COVID-19. MRI also showed a well-enhanced hyperintense lesion in the left orbital apex. Fortunately, her visual acuity and ocular motility returned to normal after the steroid therapy. Conclusions: Immunologic reactions from COVID-19 vaccines may cause multiple cranial neuropathies. Diverse individual immunologic states should be considered before any kind of vaccine.http://www.sciencedirect.com/science/article/pii/S2405650223000059Orbital apex syndromeDiplopiaOphthalmoplegiaCOVID-19SARS-CoV-2Vaccination |
| spellingShingle | Seo-Young Choi Jae-Hwan Choi Eun Hye Oh Kwang-Dong Choi Sequential orbital apex syndrome following the COVID-19 vaccination: A case report eNeurologicalSci Orbital apex syndrome Diplopia Ophthalmoplegia COVID-19 SARS-CoV-2 Vaccination |
| title | Sequential orbital apex syndrome following the COVID-19 vaccination: A case report |
| title_full | Sequential orbital apex syndrome following the COVID-19 vaccination: A case report |
| title_fullStr | Sequential orbital apex syndrome following the COVID-19 vaccination: A case report |
| title_full_unstemmed | Sequential orbital apex syndrome following the COVID-19 vaccination: A case report |
| title_short | Sequential orbital apex syndrome following the COVID-19 vaccination: A case report |
| title_sort | sequential orbital apex syndrome following the covid 19 vaccination a case report |
| topic | Orbital apex syndrome Diplopia Ophthalmoplegia COVID-19 SARS-CoV-2 Vaccination |
| url | http://www.sciencedirect.com/science/article/pii/S2405650223000059 |
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