Establishment and Validation of a New Co-Culture for the Evaluation of the Permeability through the Blood–Brain Barrier in Patients with Glioblastoma
Currently, the mechanisms involved in drug access to the central nervous system (CNS) are not completely elucidated, and research efforts to understand the behaviour of the therapeutic agents to access the blood–brain barrier continue with the utmost importance. The aim of this work was the creation...
Main Authors: | Bárbara Sánchez-Dengra, Elena García-Montoya, Isabel González-Álvarez, Marival Bermejo, Marta González-Álvarez |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-05-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/15/5/1431 |
Similar Items
-
Candesartan Cilexetil In Vitro–In Vivo Correlation: Predictive Dissolution as a Development Tool
by: Andrés Figueroa-Campos, et al.
Published: (2020-07-01) -
In Vivo Relevance of a Biphasic In Vitro Dissolution Test for the Immediate Release Tablet Formulations of Lamotrigine
by: Tuba Incecayir, et al.
Published: (2023-10-01) -
Brain targeted delivery of paclitaxel using endogenous ligand
by: Sanjeev R. Acharya, et al.
Published: (2016-06-01) -
PerfuPul—A Versatile Perfusable Platform to Assess Permeability and Barrier Function of Air Exposed Pulmonary Epithelia
by: Patrick Carius, et al.
Published: (2021-10-01) -
In Vitro–In Vivo Correlations Based on In Vitro Dissolution of Parent Drug Diltiazem and Pharmacokinetics of Its Metabolite
by: Constantin Mircioiu, et al.
Published: (2019-07-01)