The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
Aimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2005-12-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/3692 |
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author | T. A. Zamoshchina Kh. M. Shraim Ye. V. Ivanova |
author_facet | T. A. Zamoshchina Kh. M. Shraim Ye. V. Ivanova |
author_sort | T. A. Zamoshchina |
collection | DOAJ |
description | Aimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined on the flaming photometer of “Karl Zeiss” firm. Lithium oxybutirate slowed down rhythmic change of sodium level in blood and brain, potassium level in brain and lithium level in urine to endogenous mode. The drug promoted accumulation of sodium and lithium in brain tissue while preserving level of calcium and potassium unchanged; potassium was redistributed into peripheral tissues. |
first_indexed | 2024-04-10T01:14:00Z |
format | Article |
id | doaj.art-5b634f0df1764eb6a8ceadd8471649c6 |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:14:00Z |
publishDate | 2005-12-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-5b634f0df1764eb6a8ceadd8471649c62023-03-13T09:58:04ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842005-12-0144354210.20538/1682-0363-2005-4-35-422331The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solsticeT. A. Zamoshchina0Kh. M. Shraim1Ye. V. Ivanova2Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетAimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined on the flaming photometer of “Karl Zeiss” firm. Lithium oxybutirate slowed down rhythmic change of sodium level in blood and brain, potassium level in brain and lithium level in urine to endogenous mode. The drug promoted accumulation of sodium and lithium in brain tissue while preserving level of calcium and potassium unchanged; potassium was redistributed into peripheral tissues.https://bulletin.ssmu.ru/jour/article/view/3692циркадный ритмнатрийкалийкальцийлитийкровьмозгмоча |
spellingShingle | T. A. Zamoshchina Kh. M. Shraim Ye. V. Ivanova The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice Бюллетень сибирской медицины циркадный ритм натрий калий кальций литий кровь мозг моча |
title | The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice |
title_full | The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice |
title_fullStr | The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice |
title_full_unstemmed | The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice |
title_short | The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice |
title_sort | influence of lithium oxybutirate on the rhythmic organization of daily dynamics of na sup sup k sup sup ca sup 2 sup and li sup sup contents in blood brain and urine of rats during summer solstice |
topic | циркадный ритм натрий калий кальций литий кровь мозг моча |
url | https://bulletin.ssmu.ru/jour/article/view/3692 |
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