The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice

Aimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined...

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Main Authors: T. A. Zamoshchina, Kh. M. Shraim, Ye. V. Ivanova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2005-12-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3692
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author T. A. Zamoshchina
Kh. M. Shraim
Ye. V. Ivanova
author_facet T. A. Zamoshchina
Kh. M. Shraim
Ye. V. Ivanova
author_sort T. A. Zamoshchina
collection DOAJ
description Aimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined on the flaming photometer of “Karl Zeiss” firm. Lithium oxybutirate slowed down rhythmic change of sodium level in blood and brain, potassium level in brain and lithium level in urine to endogenous mode. The drug promoted accumulation of sodium and lithium in brain tissue while preserving level of calcium and potassium unchanged; potassium was redistributed into peripheral tissues.
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spelling doaj.art-5b634f0df1764eb6a8ceadd8471649c62023-03-13T09:58:04ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842005-12-0144354210.20538/1682-0363-2005-4-35-422331The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solsticeT. A. Zamoshchina0Kh. M. Shraim1Ye. V. Ivanova2Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетAimed at studying the influence of lithium oxybutirate on rhythmic organization of daily dynamics of Na+, K+, Ca2+ and Li+ contents in blood, brain and urine of rats during summer solstice, experiments on 84 male rats were performed. Cations’ content in blood, brain and urine of rats was determined on the flaming photometer of “Karl Zeiss” firm. Lithium oxybutirate slowed down rhythmic change of sodium level in blood and brain, potassium level in brain and lithium level in urine to endogenous mode. The drug promoted accumulation of sodium and lithium in brain tissue while preserving level of calcium and potassium unchanged; potassium was redistributed into peripheral tissues.https://bulletin.ssmu.ru/jour/article/view/3692циркадный ритмнатрийкалийкальцийлитийкровьмозгмоча
spellingShingle T. A. Zamoshchina
Kh. M. Shraim
Ye. V. Ivanova
The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
Бюллетень сибирской медицины
циркадный ритм
натрий
калий
кальций
литий
кровь
мозг
моча
title The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
title_full The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
title_fullStr The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
title_full_unstemmed The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
title_short The influence of lithium oxybutirate on the rhythmic organization of daily dynamics of Na<sup>+</sup>, K<sup>+</sup>, Ca<sup>2+</sup> and Li<sup>+</sup> contents in blood, brain and urine of rats during summer solstice
title_sort influence of lithium oxybutirate on the rhythmic organization of daily dynamics of na sup sup k sup sup ca sup 2 sup and li sup sup contents in blood brain and urine of rats during summer solstice
topic циркадный ритм
натрий
калий
кальций
литий
кровь
мозг
моча
url https://bulletin.ssmu.ru/jour/article/view/3692
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