Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level
Epidemiological data leaves no illusions – diabetes mellitus is a real epidemic of a non-communicable disease. Glycated haemoglobin was isolated with chromatography column as a separate subtype of haemoglobin as early as in 1958. An increase in its concentration in response to hyperglycaemia has al...
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2018-12-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/25970 |
| _version_ | 1818009883458404352 |
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| author | Marcin Lewicki Łukasz Chołuj Marta Molendowska Zuzanna Czarnota Rafał Mazur Mateusz Tyniec Agata Barbara Smoleń |
| author_facet | Marcin Lewicki Łukasz Chołuj Marta Molendowska Zuzanna Czarnota Rafał Mazur Mateusz Tyniec Agata Barbara Smoleń |
| author_sort | Marcin Lewicki |
| collection | DOAJ |
| description | Epidemiological data leaves no illusions – diabetes mellitus is a real epidemic of a non-communicable disease. Glycated haemoglobin was isolated with chromatography column as a separate subtype of haemoglobin as early as in 1958. An increase in its concentration in response to hyperglycaemia has already been recognized in 1969. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control in patients with diabetes. With HbA1C measurement we are able to retrospectively assess the average blood glucose levels. HbA1c correlates well with the risk of long-term diabetes complications. However, HbA1C levels may sometimes be misleading as a reliable measure of glycemic control. HbA1c values measurements are prone to diagnostic interference with many factors. The aim of this review was to present the numerous clinical scenarios in which the use of HbA1c levels alone for either diagnosis or as a marker of glycemic control, may lead to false assumptions. |
| first_indexed | 2024-04-14T05:48:31Z |
| format | Article |
| id | doaj.art-5b651d0dacca455dba2e155a92fca324 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-14T05:48:31Z |
| publishDate | 2018-12-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-5b651d0dacca455dba2e155a92fca3242022-12-22T02:09:13ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-12-01812Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c levelMarcin Lewicki0Łukasz Chołuj1Marta Molendowska2Zuzanna Czarnota3Rafał Mazur4Mateusz Tyniec5Agata Barbara Smoleń6Chair and Department of Epidemiology and Clinical Research Methodology of the Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Student Scientific Association at Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Student Scientific Association at Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Student Scientific Association at Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Student Scientific Association at Department of Epidemiology and Clinical Research Methodology, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Chair and Department of Epidemiology and Clinical Research Methodology of the Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Chair and Department of Epidemiology and Clinical Research Methodology of the Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080Epidemiological data leaves no illusions – diabetes mellitus is a real epidemic of a non-communicable disease. Glycated haemoglobin was isolated with chromatography column as a separate subtype of haemoglobin as early as in 1958. An increase in its concentration in response to hyperglycaemia has already been recognized in 1969. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control in patients with diabetes. With HbA1C measurement we are able to retrospectively assess the average blood glucose levels. HbA1c correlates well with the risk of long-term diabetes complications. However, HbA1C levels may sometimes be misleading as a reliable measure of glycemic control. HbA1c values measurements are prone to diagnostic interference with many factors. The aim of this review was to present the numerous clinical scenarios in which the use of HbA1c levels alone for either diagnosis or as a marker of glycemic control, may lead to false assumptions.https://apcz.umk.pl/JEHS/article/view/25970glycated haemoglobinHbA1Cdiabetes mellitus |
| spellingShingle | Marcin Lewicki Łukasz Chołuj Marta Molendowska Zuzanna Czarnota Rafał Mazur Mateusz Tyniec Agata Barbara Smoleń Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level Journal of Education, Health and Sport glycated haemoglobin HbA1C diabetes mellitus |
| title | Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level |
| title_full | Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level |
| title_fullStr | Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level |
| title_full_unstemmed | Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level |
| title_short | Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level |
| title_sort | glycated haemoglobin when can we trust it analysis of factors affecting the hba1c level |
| topic | glycated haemoglobin HbA1C diabetes mellitus |
| url | https://apcz.umk.pl/JEHS/article/view/25970 |
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