Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status
Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-05-01
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| Series: | Nutrition and Metabolic Insights |
| Online Access: | https://doi.org/10.1177/11786388211018726 |
| _version_ | 1819094086937739264 |
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| author | Hedyeh Saneifard Marjan Shakiba Ali Sheikhy Leila Baniadam Fatemeh Abdollah Gorji Aida Fallahzadeh |
| author_facet | Hedyeh Saneifard Marjan Shakiba Ali Sheikhy Leila Baniadam Fatemeh Abdollah Gorji Aida Fallahzadeh |
| author_sort | Hedyeh Saneifard |
| collection | DOAJ |
| description | Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level. Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020. Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese ( P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls ( P < .001). Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups. |
| first_indexed | 2024-12-21T23:21:49Z |
| format | Article |
| id | doaj.art-5b685d649efc4c62aa4edef32e3ff82f |
| institution | Directory Open Access Journal |
| issn | 1178-6388 |
| language | English |
| last_indexed | 2024-12-21T23:21:49Z |
| publishDate | 2021-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Nutrition and Metabolic Insights |
| spelling | doaj.art-5b685d649efc4c62aa4edef32e3ff82f2022-12-21T18:46:46ZengSAGE PublishingNutrition and Metabolic Insights1178-63882021-05-011410.1177/11786388211018726Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D StatusHedyeh Saneifard0Marjan Shakiba1Ali Sheikhy2Leila Baniadam3Fatemeh Abdollah Gorji4Aida Fallahzadeh5Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranMofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranTehran Heart Center (THC), Tehran University of Medical Sciences, Tehran, IranDepartment of Allergy and Clinical Immunology, Rasool-E-Akram Hospital, Iran University of Medical Sciences, Tehran, IranMedical Research Development Center, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranTehran Heart Center (THC), Tehran University of Medical Sciences, Tehran, IranBackground: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity. Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level. Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020. Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese ( P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) ( P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) ( P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls ( P < .001). Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.https://doi.org/10.1177/11786388211018726 |
| spellingShingle | Hedyeh Saneifard Marjan Shakiba Ali Sheikhy Leila Baniadam Fatemeh Abdollah Gorji Aida Fallahzadeh Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status Nutrition and Metabolic Insights |
| title | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
| title_full | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
| title_fullStr | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
| title_full_unstemmed | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
| title_short | Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status |
| title_sort | vitamin d deficiency in children and adolescents role of puberty and obesity on vitamin d status |
| url | https://doi.org/10.1177/11786388211018726 |
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