Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment

Patients undergoing complex percutaneous coronary intervention (PCI) are at an increased risk of atherothrombotic complications. Although dual antiplatelet therapy is the mainstay of treatment for patients undergoing PCI with stent implantation, deciding its type and duration in complex PCI patients...

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Main Authors: Despoina-Rafailia Benetou, Charalampos Varlamos, Christos Pappas, Fotios Kolokathis, Dimitrios Alexopoulos
Format: Article
Language:English
Published: Radcliffe Medical Media 2021-10-01
Series:US Cardiology Review
Online Access:https://www.uscjournal.com/articleindex/usc.2020.30
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author Despoina-Rafailia Benetou
Charalampos Varlamos
Christos Pappas
Fotios Kolokathis
Dimitrios Alexopoulos
author_facet Despoina-Rafailia Benetou
Charalampos Varlamos
Christos Pappas
Fotios Kolokathis
Dimitrios Alexopoulos
author_sort Despoina-Rafailia Benetou
collection DOAJ
description Patients undergoing complex percutaneous coronary intervention (PCI) are at an increased risk of atherothrombotic complications. Although dual antiplatelet therapy is the mainstay of treatment for patients undergoing PCI with stent implantation, deciding its type and duration in complex PCI patients has long been considered a challenge for clinicians. This is because the beneficial effects of prolonged treatment and/or more potent antiplatelet agents’ use in preventing ischemic events are hindered by a concomitant increase in bleeding complications. The aim of this review is to highlight current evidence regarding the optimal antithrombotic therapy regimens used in complex PCI patients, focusing on the evaluation of both safety and efficacy outcomes as well as addressing future perspectives.
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spelling doaj.art-5b6f64e6a44a4cc9b162c9ac93c3aff02024-04-20T16:02:24ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2021-10-011510.15420/usc.2020.30Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of TreatmentDespoina-Rafailia Benetou0Charalampos Varlamos1Christos Pappas2Fotios Kolokathis3Dimitrios Alexopoulos4Second Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreecePatients undergoing complex percutaneous coronary intervention (PCI) are at an increased risk of atherothrombotic complications. Although dual antiplatelet therapy is the mainstay of treatment for patients undergoing PCI with stent implantation, deciding its type and duration in complex PCI patients has long been considered a challenge for clinicians. This is because the beneficial effects of prolonged treatment and/or more potent antiplatelet agents’ use in preventing ischemic events are hindered by a concomitant increase in bleeding complications. The aim of this review is to highlight current evidence regarding the optimal antithrombotic therapy regimens used in complex PCI patients, focusing on the evaluation of both safety and efficacy outcomes as well as addressing future perspectives.https://www.uscjournal.com/articleindex/usc.2020.30
spellingShingle Despoina-Rafailia Benetou
Charalampos Varlamos
Christos Pappas
Fotios Kolokathis
Dimitrios Alexopoulos
Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
US Cardiology Review
title Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
title_full Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
title_fullStr Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
title_full_unstemmed Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
title_short Antithrombotics in Complex Percutaneous Coronary Interventions: Type and Duration of Treatment
title_sort antithrombotics in complex percutaneous coronary interventions type and duration of treatment
url https://www.uscjournal.com/articleindex/usc.2020.30
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