Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
The analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03879-8 |
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author | Haruki Nishimura Mitsuhiro Yoshimura Makiko Shimizu Kenya Sanada Satomi Sonoda Kazuaki Nishimura Kazuhiko Baba Naofumi Ikeda Yasuhito Motojima Takashi Maruyama Yuki Nonaka Ryoko Baba Tatsushi Onaka Takafumi Horishita Hiroyuki Morimoto Yasuhiro Yoshida Makoto Kawasaki Akinori Sakai Masafumi Muratani Becky Conway-Campbell Stafford Lightman Yoichi Ueta |
author_facet | Haruki Nishimura Mitsuhiro Yoshimura Makiko Shimizu Kenya Sanada Satomi Sonoda Kazuaki Nishimura Kazuhiko Baba Naofumi Ikeda Yasuhito Motojima Takashi Maruyama Yuki Nonaka Ryoko Baba Tatsushi Onaka Takafumi Horishita Hiroyuki Morimoto Yasuhiro Yoshida Makoto Kawasaki Akinori Sakai Masafumi Muratani Becky Conway-Campbell Stafford Lightman Yoichi Ueta |
author_sort | Haruki Nishimura |
collection | DOAJ |
description | The analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response. |
first_indexed | 2024-12-10T14:42:33Z |
format | Article |
id | doaj.art-5b705d17b31d48fe8095a53fc1367b16 |
institution | Directory Open Access Journal |
issn | 2399-3642 |
language | English |
last_indexed | 2024-12-10T14:42:33Z |
publishDate | 2022-09-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Biology |
spelling | doaj.art-5b705d17b31d48fe8095a53fc1367b162022-12-22T01:44:39ZengNature PortfolioCommunications Biology2399-36422022-09-015111910.1038/s42003-022-03879-8Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in ratsHaruki Nishimura0Mitsuhiro Yoshimura1Makiko Shimizu2Kenya Sanada3Satomi Sonoda4Kazuaki Nishimura5Kazuhiko Baba6Naofumi Ikeda7Yasuhito Motojima8Takashi Maruyama9Yuki Nonaka10Ryoko Baba11Tatsushi Onaka12Takafumi Horishita13Hiroyuki Morimoto14Yasuhiro Yoshida15Makoto Kawasaki16Akinori Sakai17Masafumi Muratani18Becky Conway-Campbell19Stafford Lightman20Yoichi Ueta21Department of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Anatomy (II), School of Medicine, University of Occupational and Environmental HealthDivision of Brain and Neurophysiology, Department of Physiology, Jichi Medical UniversityDepartment of Anesthesiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Anatomy (II), School of Medicine, University of Occupational and Environmental HealthDepartment of Immunology and Parasitology, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthGenome Biology, Faculty of Medicine, University of TsukubaTranslational Health Sciences, Bristol Medical School, University of BristolTranslational Health Sciences, Bristol Medical School, University of BristolDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthThe analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.https://doi.org/10.1038/s42003-022-03879-8 |
spellingShingle | Haruki Nishimura Mitsuhiro Yoshimura Makiko Shimizu Kenya Sanada Satomi Sonoda Kazuaki Nishimura Kazuhiko Baba Naofumi Ikeda Yasuhito Motojima Takashi Maruyama Yuki Nonaka Ryoko Baba Tatsushi Onaka Takafumi Horishita Hiroyuki Morimoto Yasuhiro Yoshida Makoto Kawasaki Akinori Sakai Masafumi Muratani Becky Conway-Campbell Stafford Lightman Yoichi Ueta Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats Communications Biology |
title | Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats |
title_full | Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats |
title_fullStr | Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats |
title_full_unstemmed | Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats |
title_short | Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats |
title_sort | endogenous oxytocin exerts anti nociceptive and anti inflammatory effects in rats |
url | https://doi.org/10.1038/s42003-022-03879-8 |
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