Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats

The analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.

Bibliographic Details
Main Authors: Haruki Nishimura, Mitsuhiro Yoshimura, Makiko Shimizu, Kenya Sanada, Satomi Sonoda, Kazuaki Nishimura, Kazuhiko Baba, Naofumi Ikeda, Yasuhito Motojima, Takashi Maruyama, Yuki Nonaka, Ryoko Baba, Tatsushi Onaka, Takafumi Horishita, Hiroyuki Morimoto, Yasuhiro Yoshida, Makoto Kawasaki, Akinori Sakai, Masafumi Muratani, Becky Conway-Campbell, Stafford Lightman, Yoichi Ueta
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03879-8
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author Haruki Nishimura
Mitsuhiro Yoshimura
Makiko Shimizu
Kenya Sanada
Satomi Sonoda
Kazuaki Nishimura
Kazuhiko Baba
Naofumi Ikeda
Yasuhito Motojima
Takashi Maruyama
Yuki Nonaka
Ryoko Baba
Tatsushi Onaka
Takafumi Horishita
Hiroyuki Morimoto
Yasuhiro Yoshida
Makoto Kawasaki
Akinori Sakai
Masafumi Muratani
Becky Conway-Campbell
Stafford Lightman
Yoichi Ueta
author_facet Haruki Nishimura
Mitsuhiro Yoshimura
Makiko Shimizu
Kenya Sanada
Satomi Sonoda
Kazuaki Nishimura
Kazuhiko Baba
Naofumi Ikeda
Yasuhito Motojima
Takashi Maruyama
Yuki Nonaka
Ryoko Baba
Tatsushi Onaka
Takafumi Horishita
Hiroyuki Morimoto
Yasuhiro Yoshida
Makoto Kawasaki
Akinori Sakai
Masafumi Muratani
Becky Conway-Campbell
Stafford Lightman
Yoichi Ueta
author_sort Haruki Nishimura
collection DOAJ
description The analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.
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spelling doaj.art-5b705d17b31d48fe8095a53fc1367b162022-12-22T01:44:39ZengNature PortfolioCommunications Biology2399-36422022-09-015111910.1038/s42003-022-03879-8Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in ratsHaruki Nishimura0Mitsuhiro Yoshimura1Makiko Shimizu2Kenya Sanada3Satomi Sonoda4Kazuaki Nishimura5Kazuhiko Baba6Naofumi Ikeda7Yasuhito Motojima8Takashi Maruyama9Yuki Nonaka10Ryoko Baba11Tatsushi Onaka12Takafumi Horishita13Hiroyuki Morimoto14Yasuhiro Yoshida15Makoto Kawasaki16Akinori Sakai17Masafumi Muratani18Becky Conway-Campbell19Stafford Lightman20Yoichi Ueta21Department of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthThe First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Anatomy (II), School of Medicine, University of Occupational and Environmental HealthDivision of Brain and Neurophysiology, Department of Physiology, Jichi Medical UniversityDepartment of Anesthesiology, School of Medicine, University of Occupational and Environmental HealthDepartment of Anatomy (II), School of Medicine, University of Occupational and Environmental HealthDepartment of Immunology and Parasitology, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental HealthGenome Biology, Faculty of Medicine, University of TsukubaTranslational Health Sciences, Bristol Medical School, University of BristolTranslational Health Sciences, Bristol Medical School, University of BristolDepartment of Physiology, School of Medicine, University of Occupational and Environmental HealthThe analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.https://doi.org/10.1038/s42003-022-03879-8
spellingShingle Haruki Nishimura
Mitsuhiro Yoshimura
Makiko Shimizu
Kenya Sanada
Satomi Sonoda
Kazuaki Nishimura
Kazuhiko Baba
Naofumi Ikeda
Yasuhito Motojima
Takashi Maruyama
Yuki Nonaka
Ryoko Baba
Tatsushi Onaka
Takafumi Horishita
Hiroyuki Morimoto
Yasuhiro Yoshida
Makoto Kawasaki
Akinori Sakai
Masafumi Muratani
Becky Conway-Campbell
Stafford Lightman
Yoichi Ueta
Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Communications Biology
title Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
title_full Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
title_fullStr Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
title_full_unstemmed Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
title_short Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
title_sort endogenous oxytocin exerts anti nociceptive and anti inflammatory effects in rats
url https://doi.org/10.1038/s42003-022-03879-8
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