Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling – A Bioinformatics Analysis of MicroRNAs and mRNAs Network

Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling – A Bioinformatics Analysis of MicroRNAs and mRNAs Network

ObjectiveTo investigate the impact of JTXK granule on the miRNA expression profiles in hepatic tissue of diabetic mice, and to explore the molecular targets and associated signaling pathways of JTXK granule in its anti-diabetic effect.MethodsEight mice were randomly selected as normal group fed with...

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Bibliographic Details
Main Authors: Ying Bai, Xueli Bao, Guangjian Jiang, Dongyu Ge, Weipeng He, Dandan Zhao, Yi Zhang, Ruijuan Dong, Jing Hua, Nan Yang, Fangfang Mo, Sihua Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
Jiang Tang Xiao Ke Granule
bioinformatic analysis
microRNAs
anti-diabetic effect
diabetes mellitus
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00173/full

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